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NOD1antagonist-1 (compound 37) acts as an antagonist to NOD1 and exhibits a slight selectivity between NOD1 and NOD2, with IC50 values of 9.18 μM and 20.8 μM, respectively.
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| Description | NOD1antagonist-1 (compound 37) acts as an antagonist to NOD1 and exhibits a slight selectivity between NOD1 and NOD2, with IC50 values of 9.18 μM and 20.8 μM, respectively. |
| Targets&IC50 | NOD1:9.18 μM, NOD2:20.8 μM |
| In vitro | NOD1 antagonist-1 (25 μM, 1 h) suppresses the transcriptional activation of NF-kB in HEK-Blue cells and exhibits low toxicity (25 μM, 18 h). |
| Formula | C24H32N4O2S |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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