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Capecitabine-2',3'-cyclic Carbonate

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Catalog No. T64318Cas No. 921769-65-5

Capecitabine-2',3'-cyclic Carbonate is a antiproliferative agent.

Capecitabine-2',3'-cyclic Carbonate

Capecitabine-2',3'-cyclic Carbonate

🥰Excellent
Purity: 99.72%
Catalog No. T64318Cas No. 921769-65-5
Capecitabine-2',3'-cyclic Carbonate is a antiproliferative agent.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$40-In Stock
50 mg$56-In Stock
1 mL x 10 mM (in DMSO)$39-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.72%
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Product Introduction

Bioactivity
Description
Capecitabine-2',3'-cyclic Carbonate is a antiproliferative agent.
In vitro
Capecitabine-2',3'-cyclic Carbonate inhibits the proliferation of tumor cells with IC50 of 0.08mg/mL, 0.08mg/mL, 0.14mg/mL and 0.18mg/mL for HeLa, MCF-7, PZ-HPV-7 and NCI-69, respectively[1].
Chemical Properties
Molecular Weight385.34
FormulaC16H20FN3O7
Cas No.921769-65-5
SmilesO=C1N([C@H]2[C@]3([C@@]([C@@H](C)O2)(OC(=O)O3)[H])[H])C=C(F)C(NC(OCCCCC)=O)=N1
Relative Density.1.58 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 27.5 mg/mL (71.37 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5951 mL12.9756 mL25.9511 mL129.7555 mL
5 mM0.5190 mL2.5951 mL5.1902 mL25.9511 mL
10 mM0.2595 mL1.2976 mL2.5951 mL12.9756 mL
20 mM0.1298 mL0.6488 mL1.2976 mL6.4878 mL
50 mM0.0519 mL0.2595 mL0.5190 mL2.5951 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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