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C-Type Natriuretic Peptide (1-22) acetate（human） (Synonyms: C-Type Natriuretic Peptide (CNP) (1-22), human aceta...)

Name: C-Type Natriuretic Peptide (1-22) acetate（human）
Brand: TargetMol
SKU: T39392L
Price: 57 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T39392L Copy Product Info

Purity: 95.95%

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C-Type Natriuretic Peptide (CNP) (1-22), human acetate is an agonist of natriuretic peptide receptor B (NPR-B), an endothelial-derived relaxant and growth inhibitory factor. C-Type Natriuretic Peptide (CNP) (1-22), human acetate inhibits cAMP synthesis stimulated by histamine and 5-HT or directly by Forskolin.

C-Type Natriuretic Peptide (1-22) acetate（human）

Copy Product Info

🥰Excellent

Catalog No. T39392L

Synonyms C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base)

C-Type Natriuretic Peptide (1-22) acetate（human）

Pack Size	Price	USA Stock	Global Stock
1 mg	$57	In Stock	In Stock
5 mg	$229	In Stock	In Stock
10 mg	$330	-	In Stock
25 mg	$498	-	In Stock
50 mg	$685	-	In Stock
100 mg	$917	-	In Stock
200 mg	$1,230	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:95.95%

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COA HPLC MS

Product Introduction

Bioactivity

Description	C-Type Natriuretic Peptide (CNP) (1-22), human acetate is an agonist of natriuretic peptide receptor B (NPR-B), an endothelial-derived relaxant and growth inhibitory factor. C-Type Natriuretic Peptide (CNP) (1-22), human acetate inhibits cAMP synthesis stimulated by histamine and 5-HT or directly by Forskolin.
In vitro	In CHO cells expressing human NPR-B, C-Type Natriuretic Peptide (CNP) (1-22), human acetate (0.01, 0.1, 1, 10, 100, 1000 nM) increased cGMP production in a concentration-dependent manner[2].
In vivo	C-Type Natriuretic Peptide (CNP) (1-22), human acetate (2 nM; i.c.v.) induced an increase in the severity of picrotoxin-kindled convulsions 24 hours after application of the peptide[3].
Synonyms	C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base)

Chemical Properties

Molecular Weight	2371.68
Formula	C₉₇H₁₆₂F₃N₂₇O₃₂S₃
Smiles	CC(O)=O.FC(F)(F)C(O)=O.O=C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@](C(NCC1=O)=O)([H])[C@@H](C)CC)=O)CCCNC(N)=N)=O)CC(O)=O)=O)CC(C)C)=O)CCCCN)=O)CC(C)C)=O)[C@](NC([C@H](CSSC[C@H](NC(CNC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CO)N1)=O)CCSC)=O)CO)=O)=O)CC(C)C)=O)=O)C(O)=O)NC(CNC([C@H](CCCCN)NC([C@H](CO)NC([C@H](CC(C)C)NC(CN)=O)=O)=O)=O)=O)=O)([H])CC2=CC=CC=C2
Sequence	Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys
Sequence Short	GLSKGCFGLKLDRIGSMSGLGC

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

NPR-BC-Type Natriuretic Peptide (CNP) , human AcetateCType Natriuretic Peptide (CNP) (122), human acetateC Type Natriuretic Peptide (CNP) (1 22), human acetate

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