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Ukrain

Catalog No. T34996 CAS 138069-52-0

Synonyms: NSC631570, NSC 631570, NSC-631570

Ukrain, also known as NSC-631570, is claimed to be a semisynthetic compound of thiophosphoric acid (triaziridide) and the alkaloid chelidonine derived from the common weed, Chelidonium majus (greater celandine), which grows primarily in Europe and Asia.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Ukrain, CAS 138069-52-0

Pack Size	Availability	Price/USD	Quantity
25 mg	Inquiry	$ 1,520.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	NSC631570, NSC 631570, NSC-631570
Molecular Weight	1269.37
Formula	C66H73N6O16PS
CAS No.	138069-52-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Bozeman EN, Srivatsan S, Mohammadi H, Daniels D, Shashidharamurthy R, Selvaraj P. Ukrain, a plant derived semi-synthetic compound, exerts antitumor effects against murine and human breast cancer and induce protective antitumor immunity in mice. Exp Oncol. 2012 Dec;34(4):340-7. PubMed PMID: 23302993. 2. Gagliano N, Volpari T, Clerici M, Pettinari L, Barajon I, Portinaro N, Colombo G, Milzani A, Dalle-Donne I, Martinelli C. Pancreatic cancer cells retain the epithelial-related phenotype and modify mitotic spindle microtubules after the administration of ukrain in vitro. Anticancer Drugs. 2012 Oct;23(9):935-46. doi: 10.1097/CAD.0b013e32835507bc. PubMed PMID: 22700003. 3. Gagliano N, Pettinari L, Aureli M, Martinelli C, Colombo E, Costa F, Carminati R, Volpari T, Colombo G, Milzani A, Dalle-Donne I, Gioia M. Malignant phenotype of renal cell carcinoma cells is switched by ukrain administration in vitro. Anticancer Drugs. 2011 Sep;22(8):749-62. doi: 10.1097/CAD.0b013e328346c7f7. PubMed PMID: 21799470. 4. Venkatesh K, Govindaraj S, Ramachandran A, Kalimuthu S, Perumal E, Velayutham S, Jagadeesan A. Effect of ukrain on cell survival and apoptosis in the androgen-independent prostate cancer cell line PC-3. J Environ Pathol Toxicol Oncol. 2011;30(1):11-9. PubMed PMID: 21609312.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ukrain 138069-52-0 NSC631570 NSC 631570 NSC-631570 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.