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SC 32855

Catalog No. T34551 CAS 76053-14-0

Synonyms: SC-32855, SC32855

SC 32855 is a 1,4-benzodiazepine that has been shown to arrest of spermatogenesis and degeneration of the germinal epithelium.

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SC 32855, CAS 76053-14-0

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

SC 32855 is a 1,4-benzodiazepine that has been shown to arrest of spermatogenesis and degeneration of the germinal epithelium.

Synonyms	SC-32855, SC32855
Molecular Weight	360.24
Formula	C18H15Cl2N3O
CAS No.	76053-14-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Chengelis CP, Dodd DC, Kotsonis FN. Testicular toxicity of a novel 1,4-benzodiazepine (SC-32855) in rats and dogs. Res Commun Chem Pathol Pharmacol. 1986 Jan;51(1):23-36. PubMed PMID: 3952369. 2. Means JR, Chengelis CP, Jasty V. Testicular toxicity induced by oral administration of SC-32855, A 1,4-benzodiazepine, in the dog. Res Commun Chem Pathol Pharmacol. 1982 Aug;37(2):317-20. PubMed PMID: 6127762. 3. Piotrowska A, Kwiatkowski K, Rojewska E, Slusarczyk J, Makuch W, Basta-Kaim A, Przewlocka B, Mika J. Direct and indirect pharmacological modulation of CCL2/CCR2 pathway results in attenuation of neuropathic pain - In vivo and in vitro evidence. J Neuroimmunol. 2016 Aug 15;297:9-19. doi: 10.1016/j.jneuroim.2016.04.017. Epub 2016 May 3. PubMed PMID: 27397071.

Dose Conversion

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

SC 32855 76053-14-0 SC-32855 SC32855 inhibitor inhibit

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