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SB 201823-A

Catalog No. T28668   CAS 141429-64-3
Synonyms: SB201823A, SB-201823-A

SB 201823-A is a Ca2+ channel antagonist.

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SB 201823-A Chemical Structure
SB 201823-A, CAS 141429-64-3
Pack Size Availability Price/USD Quantity
5 mg 6-8 weeks $ 970.00
50 mg 6-8 weeks $ 1,980.00
100 mg 6-8 weeks $ 2,500.00
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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.
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Biological Description
Chemical Properties
Storage & Solubility Information
Description SB 201823-A is a Ca2+ channel antagonist.
Synonyms SB201823A, SB-201823-A
Molecular Weight 380.78
Formula C18H28Cl3NO
CAS No. 141429-64-3


Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

TargetMolReferences and Literature

1. Hicks CA, Ward MA, O'Neill MJ. Neuroprotective effects of the neuronal Ca(2+) channel blockers, LY042826 and LY393615 in vivo. Eur J Pharmacol. 2000 Nov 24;408(3):241-8. PubMed PMID: 11090640. 2. O'Neill MJ, Bath CP, Dell CP, Hicks CA, Gilmore J, Ambler SJ, Ward MA, Bleakman D. Effects of Ca2+ and Na+ channel inhibitors in vitro and in global cerebral ischaemia in vivo. Eur J Pharmacol. 1997 Aug 6;332(2):121-31. PubMed PMID: 9286613. 3. Barone FC, Lysko PG, Price WJ, Feuerstein G, al-Baracanji KA, Benham CD, Harrison DC, Harries MH, Bailey SJ, Hunter AJ. SB 201823-A antagonizes calcium currents in central neurons and reduces the effects of focal ischemia in rats and mice. Stroke. 1995 Sep;26(9):1683-9; discussion 1689-90. PubMed PMID: 7660415. 4. Benham CD, Brown TH, Cooper DG, Evans ML, Harries MH, Herdon HJ, Meakin JE, Murkitt KL, Patel SR, Roberts JC, et al. SB 201823-A, a neuronal Ca2+ antagonist is neuroprotective in two models of cerebral ischaemia. Neuropharmacology. 1993 Nov;32(11):1249-57. PubMed PMID: 8107976.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box


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Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box


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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.


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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.


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