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RP-101075

Catalog No. T34402 CAS T34402

Synonyms: RP101075

RP-101075 is a etabolite of Ozanimod. It exhibits a similar specificity profile as Ozanimod at the S1P Receptor family in vitro, and pharmacodynamic profile in vivo.

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RP-101075, CAS T34402

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

RP-101075 is a etabolite of Ozanimod. It exhibits a similar specificity profile as Ozanimod at the S1P receptor family in vitro, and pharmacodynamic profile in vivo.

Synonyms	RP101075
Molecular Weight	360.42
Formula	C21H20N4O2
CAS No.	T34402

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Taylor Meadows KR, Steinberg MW, Clemons B, Stokes ME, Opiteck GJ, Peach R, Scott FL. Ozanimod (RPC1063), a selective S1PR1 and S1PR5 modulator, reduces chronic inflammation and alleviates kidney pathology in murine systemic lupus erythematosus. PLoS One. 2018 Apr 2;13(4):e0193236. doi: 10.1371/journal.pone.0193236. eCollection 2018. PubMed PMID: 29608575; PubMed Central PMCID: PMC5880347.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

RP-101075 T34402 RP 101075 RP101075 inhibitor inhibit

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