Store the unopened solution at -20℃, and store it at 4℃ after melting to avoid repeated freeze-thaw
Pertuzumab anti-HER2) a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors impairs the ability of HER2 to bind to other members of the HER family.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | 558.00 |
Description | Pertuzumab anti-HER2) a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors impairs the ability of HER2 to bind to other members of the HER family. |
Targets&IC50 | HER2 |
Cell Research |
Objective: Antibody-dependent cellular cytotoxicity (ADCC)
Concentrations: 2.5 μg/mL
Incubation Time: --
Method: A standard 5 h chromium (51Cr) release assay was performed to measure the cytotoxic reactivity of peripheral blood lymphocytes (PBLs) from several healthy donors in combination with trastuzumab and/or pertuzumab against USPC target cell lines.
Cell lines: peripheral blood lymphocytes (PBLs), USPC cell lines (Uterine cancer cell)
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Animal Research |
Objective: In vivo tumor growth inhibition studies
Formulation: saline
Dosages: 20 mg/kg, 40 mg/kg and 80 mg/kg
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Synonyms | Pertuzumab (anti-HER2) , anti-HER2 , Omnitarg , 2C4 |
Purity | 98.3% |
Molecular Weight | N/A |
CAS No. | 380610-27-5 |
Store the unopened solution at -20℃, and store it at 4℃ after melting to avoid repeated freeze-thaw
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.