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Pentetreotide

Catalog No. T16469 CAS 138661-02-6

Pentetreotide is an indium-labeled somatostatin analog and can be used for nuclear medicine imaging. Pentetreotide is a diethylenetriaminopentaacetic conjugate of Octreotide. Somatostatin receptor scintigraphy with Pentetreotide is effective in visualizing neuroendocrine tumors, and its metastasis.

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Pentetreotide, CAS 138661-02-6

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Biological Description

Chemical Properties

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Description

In vitro

Somatostatin receptor scintigraphy with 111In-Pentetreotide binds to two of these subtypes and is effective in visualizing neuroendocrine tumors, and its metastasis with an overall diagnostic sensitivity of 70% to 90%. Its usage in neuroendocrine tumors not only includes an assessment of disease extent, but also in the identified primary lesion, assesses treatment response, and selection for radionuclide therapy[1].

Molecular Weight	1394.58
Formula	C63H87N13O19S2
CAS No.	138661-02-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Al-Suqri B. 111 In-pentetreotide SPECT CT Value in Follow-up of Patients with Neuro-Endocrine Tumors. Oman Med J. 2014 Sep;29(5):362-4. 2. Masuda R, et al. Concise site-specific synthesis of DTPA-peptide conjugates: application to imaging probes for the chemokine receptor CXCR4. Bioorg Med Chem. 2011 May 15;19(10):3216-20.

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Pentetreotide 138661-02-6 Others inhibitor inhibit

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