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NMP-7

Catalog No. T25874 CAS 1358039-07-2

Synonyms: NMP 7, NMP7

NMP-7 is a non-selective CB1 and CB2 Cannabinoid Receptor agonist that works by blocking T-type calcium channels.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

NMP-7, CAS 1358039-07-2

Pack Size	Availability	Price/USD
5 mg	6-8 weeks	$ 970.00 $ 776.00
50 mg	6-8 weeks	$ 1,980.00 $ 1,584.00
100 mg	6-8 weeks	$ 2,500.00 $ 2,000.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

NMP-7 is a non-selective CB1 and CB2 cannabinoid receptor agonist that works by blocking T-type calcium channels.

Synonyms	NMP 7, NMP7
Molecular Weight	348.48
Formula	C23H28N2O
CAS No.	1358039-07-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Berger ND, Gadotti VM, Petrov RR, Chapman K, Diaz P, Zamponi GW. NMP-7 inhibits chronic inflammatory and neuropathic pain via block of Cav3.2 T-type calcium channels and activation of CB2 receptors. Mol Pain. 2014 Dec 6;10:77. doi: 10.1186/1744-8069-10-77. PubMed PMID: 25481027; PubMed Central PMCID: PMC4271433. 2. You H, Gadotti VM, Petrov RR, Zamponi GW, Diaz P. Functional characterization and analgesic effects of mixed cannabinoid receptor/T-type channel ligands. Mol Pain. 2011 Nov 17;7:89. doi: 10.1186/1744-8069-7-89. PubMed PMID: 22093952; PubMed Central PMCID: PMC3250956. 3. Little MA, Ronson TK, Hardie MJ. New coordination polymers with extended arm cyclotriguaiacyclene ligands: 1D chains, and interpenetrating or polycatenating 2D (4(2).6(2))(4.6(2))2 networks. Dalton Trans. 2011 Dec 7;40(45):12217-27. doi: 10.1039/c1dt10662g. Epub 2011 Aug 25. PubMed PMID: 21869979.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

NMP-7 1358039-07-2 NMP 7 NMP7 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.