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Histrelin

Catalog No. T21308 CAS 76712-82-8

Synonyms: Supprelin LA, Histrelin Acetate

Histrelin (Supprelin LA) acetate is a nonapeptide analog of gonadotropin-releasing hormone (GnRH) with added potency. It is considered a GnRH agonist. Histrelin is used in the treatment of hormone-sensitive cancers of the prostate in men and uterine fibroids in women.

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Histrelin, CAS 76712-82-8

Pack Size	Availability	Price/USD
2 mg	Inquiry	$ 86.00
5 mg	Inquiry	$ 110.00
10 mg	Inquiry	$ 184.00
25 mg	Inquiry	$ 339.00
50 mg	Inquiry	$ 498.00

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Purity: 99.38%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Supprelin LA, Histrelin Acetate
Molecular Weight	1323.5
Formula	C66H86N18O12
CAS No.	76712-82-8

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Soluble

H2O: Insoluble

References and Literature

1. Lewis KA, Goldyn AK, West KW, Eugster EA. A single histrelin implant is effective for 2 years for treatment of central precocious puberty. J Pediatr. 2013 Oct;163(4):1214-6. doi: 10.1016/j.jpeds.2013.05.033. Epub 2013 Jul 1. PubMed PMID: 23809043. 2. Gillis D, Karavani G, Hirsch HJ, Strich D. Time to menarche and final height after histrelin implant treatment for central precocious puberty. J Pediatr. 2013 Aug;163(2):532-6. doi: 10.1016/j.jpeds.2013.01.021. Epub 2013 Feb 26. PubMed PMID: 23485026. 3. Lewis KA, Eugster EA. Random luteinizing hormone often remains pubertal in children treated with the histrelin implant for central precocious puberty. J Pediatr. 2013 Mar;162(3):562-5. doi: 10.1016/j.jpeds.2012.08.038. Epub 2012 Oct 3. PubMed PMID: 23040793. 4. Shore N, Cookson MS, Gittelman MC. Long-term efficacy and tolerability of once-yearly histrelin acetate subcutaneous implant in patients with advanced prostate cancer. BJU Int. 2012 Jan;109(2):226-32. doi: 10.1111/j.1464-410X.2011.10370.x. Epub 2011 Aug 18. PubMed PMID: 21851539.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Histrelin 76712-82-8 Others GNRHR Gonadotropin releasing hormone receptor vasopressin Supprelin LA inhibit FSH endometriosis Prostate cancer Inhibitor H-N systerm Histrelin Acetate GnRH Receptor inhibitor

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