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Glycerol phenylbutyrate-D15

Catalog No. T19341 CAS T19341

Synonyms: HPN-100-D15

Glycerol phenylbutyrate-D15 is a deuterium-labeled Glycerol phenylbutyrate. Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand (pKi: 8.02).

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Glycerol phenylbutyrate-D15 Chemical Structure

Glycerol phenylbutyrate-D15, CAS T19341

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	Glycerol phenylbutyrate-D15 is a deuterium-labeled Glycerol phenylbutyrate. Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand (pKi: 8.02).
In vivo	Glycerol phenylbutyrate (GPB) exhibits therapeutic potential not only for hyperammonemia but also for conditions like chronic hepatic encephalopathy and various inherited metabolic disorders.

Synonyms	HPN-100-D15
Molecular Weight	545.74
Formula	C33H23D15O6
CAS No.	T19341

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Rescifina A, et al. Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis. Eur J Pharm Sci. 2017 Aug 30;106:94-101. 2. Oishi K, et al. Glycerol phenylbutyrate for the chronic management of urea cycle disorders. Expert Rev Endocrinol Metab. 2014 Sep;9(5):427-434.

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Keywords

Glycerol phenylbutyrate-D15 T19341 GPCR/G Protein Sigma receptor Glycerol phenylbutyrateD15 Glycerol phenylbutyrate D15 HPN-100-D15 Glycerol phenylbutyrate-D-15 inhibitor inhibit

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