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Gadobutrol Monohydrate

Catalog No. T8406L   CAS 198637-52-4
Synonyms: Gd-DO3A-butrol

Gadobutrol is a medicinal product used in diagnostic magnetic resonance imaging (MRI) in adults and children. It provides contrast enhancement during cranial, spinal, breast, or other investigations. In the central nervous system, Gadobutrol works by highlighting any areas with disrupted blood brain barrier (BBB) and/or abnormal vascularity. In breast tissue, Gadobutrol exposes the presence and extent of malignant breast disease. Similarly, gadobutrol is also used in contrast-enhanced magnetic resonance angiography (CE-MRA) for the diagnosis of stroke, detection of tumor perfusion, and presence of focal cerebral ischemia.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Gadobutrol Monohydrate Chemical Structure
Gadobutrol Monohydrate, CAS 198637-52-4
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25 mg Inquiry $ 1,520.00
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Biological Description
Chemical Properties
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Description Gadobutrol is a medicinal product used in diagnostic magnetic resonance imaging (MRI) in adults and children. It provides contrast enhancement during cranial, spinal, breast, or other investigations. In the central nervous system, Gadobutrol works by highlighting any areas with disrupted blood brain barrier (BBB) and/or abnormal vascularity. In breast tissue, Gadobutrol exposes the presence and extent of malignant breast disease. Similarly, gadobutrol is also used in contrast-enhanced magnetic resonance angiography (CE-MRA) for the diagnosis of stroke, detection of tumor perfusion, and presence of focal cerebral ischemia.
Synonyms Gd-DO3A-butrol
Molecular Weight 622.73
Formula C18H33GdN4O10
CAS No. 198637-52-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Melsaether AN, Kim E, Mema E, Babb J, Kim SG. Preliminary study: Breast cancers can be well seen on 3T breast MRI with a half-dose of gadobutrol. Clin Imaging. 2019 Jun 27;58:84-89. doi: 10.1016/j.clinimag.2019.06.014. [Epub ahead of print] PubMed PMID: 31279989. 2. Cheung HMC, Karanicolas PJ, Coburn N, Law C, Milot L. Late Gadolinium Hyperintensity of Suspected Colorectal Liver Metastases on Gadofosveset-Enhanced Magnetic Resonance Imaging: A Predictor of Benignity and a Potential Problem-Solving Tool. Can Assoc Radiol J. 2019 Jul 1. pii: S0846-5371(19)30011-7. doi: 10.1016/j.carj.2019.03.006. [Epub ahead of print] PubMed PMID: 31272725. 3. Kim YS, Kim M, Choi SH, You SH, Yoo RE, Kang KM, Yun TJ, Lee ST, Moon J, Shin YW. Altered Vascular Permeability in Migraine-associated Brain Regions: Evaluation with Dynamic Contrast-enhanced MRI. Radiology. 2019 Jul 2:182566. doi: 10.1148/radiol.2019182566. [Epub ahead of print] PubMed PMID: 31264949. 4. McDonald JS, Hunt CH, Kolbe AB, Schmitz JJ, Hartman RP, Maddox DE, Kallmes DF, McDonald RJ. Acute Adverse Events Following Gadolinium-based Contrast Agent Administration: A Single-Center Retrospective Study of 281 945 Injections. Radiology. 2019 Jul 2:182834. doi: 10.1148/radiol.2019182834. [Epub ahead of print] PubMed PMID: 31264948.

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Keywords

Gadobutrol Monohydrate 198637-52-4 Gd-DO3A-butrol Gadobutrol inhibitor inhibit

 

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