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GPCR/G Protein GHSR CJC-1295 acetate(863288-34-0 free base)

CJC-1295 acetate(863288-34-0 free base)

Catalog No. TP2328L   CAS TP2328L
Synonyms: DAC:GRF acetate,

CJC-1295 acetate is a synthetic analogue of growth hormone-releasing hormone (GHRH) (also known as growth hormone-releasing factor (GRF)) and a growth hormone secretagogue (GHS)

CJC-1295 acetate(863288-34-0 free base), CAS TP2328L
Pack Size Availability Price/USD Quantity
1 mg In stock 149.00
5 mg In stock 336.00
10 mg In stock 504.00
25 mg In stock 908.00
50 mg In stock 1362.00
100 mg In stock 2043.00
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Purity 98.00%
Purity 98.00%
Biological Description
Chemical Properties
Storage & Solubility Information
Description CJC-1295 acetate is a synthetic analogue of growth hormone-releasing hormone (GHRH) (also known as growth hormone-releasing factor (GRF)) and a growth hormone secretagogue (GHS)
Targets&IC50
In vitro
In vivo CJC-1295 markedly increases plasma growth hormone (GH) and insulin-like growth factor 1 (IGF-1) levels in both animals and humans.[1] With a single injection, in human subjects, CJC-1295 increases plasma GH levels by 2- to 10-fold for 6 days or longer and plasma IGF-1 levels by 0.5- to 3-fold for 9 to 11 days.[3] The drug has an estimated half-life of about 6 to 8 days in humans.[3] With multiple doses of CJC-1295, IGF-1 levels were found to remain elevated in humans for up to 28 days
Synonyms DAC:GRF acetate ,
Purity 98.00%
Molecular Weight 3428.01
Formula C154H256N44O44
CAS No. TP2328L

Storage

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Jetté L, Léger R, Thibaudeau K, Benquet C, Robitaille M, Pellerin I, et al. (July 2005). "Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog". Endocrinology. 146 (7): 3052–8. 2. Alba M, Fintini D, Sagazio A, Lawrence B, Castaigne JP, Frohman LA, Salvatori R (December 2006). "Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse". American Journal of Physiology. Endocrinology and Metabolism. 291 (6): E1290-4 3. Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA (March 2006). "Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults". The Journal of Clinical Endocrinology and Metabolism. 91 (3): 799–805.

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