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Alvameline Tartrate

Catalog No. T26604 CAS 159792-14-0

Synonyms: LU-25-109T, LU 25 109T, LU-25109T, LU 25109T

Alvameline Tartrate, a muscarinic M1 receptor agonist and M2/M3 receptor antagonist, is used potentially for treatment of urinary incontinence.

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Alvameline Tartrate, CAS 159792-14-0

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Alvameline Tartrate, a muscarinic M1 receptor agonist and M2/M3 receptor antagonist, is used potentially for treatment of urinary incontinence.

Synonyms	LU-25-109T, LU 25 109T, LU-25109T, LU 25109T
Molecular Weight	343.34
Formula	C13H21N5O6
CAS No.	159792-14-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Waldeck K, Larsson B, Sandberg B, Andersson K-. Actions of the new antimuscarinic compound Lu 25-109 on isolated human and pig detrusor. Neurourol Urodyn. 2002;21(1):92-8. PubMed PMID: 11835429. 2. Sveigaard HH, Dalgaard L. Evaluation of blood-brain barrier passage of a muscarine M1 agonist and a series of analogous tetrahydropyridines measured by in vivo microdialysis. Pharm Res. 2000 Jan;17(1):70-6. PubMed PMID: 10714611. 3. Forlenza OV, Spink JM, Dayanandan R, Anderton BH, Olesen OF, Lovestone S. Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3beta inhibition and in neurons. J Neural Transm (Vienna). 2000;107(10):1201-12. PubMed PMID: 11129110. 4. Thal LJ, Forrest M, Loft H, Mengel H. Lu 25-109, a muscarinic agonist, fails to improve cognition in Alzheimer's disease. Lu25-109 Study Group. Neurology. 2000 Jan 25;54(2):421-6. PubMed PMID: 10668706.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Alvameline Tartrate 159792-14-0 LU-25-109T LU 25 109T LU-25109T LU 25109T inhibitor inhibit

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