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Adam I-123

Catalog No. T23629 CAS 305352-16-3

Synonyms: Adam I 123, Adam I123

Adam I-123 is a radiopharmaceutical containing the serotonin transporter (SERT) ligand, with SERT-binding and radioisotope activities. SERT is a monoamine transporter protein found in the membranes of neurons and platelets.

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Adam I-123, CAS 305352-16-3

Pack Size	Availability	Price/USD	Quantity
25 mg	Inquiry	$ 1,520.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Adam I 123, Adam I123
Molecular Weight	380.28
Formula	C15H17IN2S
CAS No.	305352-16-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Wu CH, Chang CS, Yang YK, Shen LH, Yao WJ. Comparison of brain serotonin transporter using [I-123]-ADAM between obese and non-obese young adults without an eating disorder. PLoS One. 2017 Feb 9;12(2):e0170886. doi: 10.1371/journal.pone.0170886. eCollection 2017. PubMed PMID: 28182708; PubMed Central PMCID: PMC5300236. 2. Huang CI, Yao WJ, Sun YN. New methods for registering long-time I-123 ADAM SPECT image sequences to magnetic resonance images. Nucl Med Commun. 2010 Aug;31(8):734-40. doi: 10.1097/MNM.0b013e32833b7534. PubMed PMID: 20505552. 3. Koch W, Schaaff N, Pöpperl G, Mulert C, Juckel G, Reicherzer M, Ehmer-von Geiso C, Möller HJ, Hegerl U, Tatsch K, Pogarell O. [I-123] ADAM and SPECT in patients with borderline personality disorder and healthy control subjects. J Psychiatry Neurosci. 2007 Jul;32(4):234-40. PubMed PMID: 17653291; PubMed Central PMCID: PMC1911193. 4. Choi SR, Hou C, Oya S, Mu M, Kung MP, Siciliano M, Acton PD, Kung HF. Selective in vitro and in vivo binding of [(125)I]ADAM to serotonin transporters in rat brain. Synapse. 2000 Dec 15;38(4):403-12. PubMed PMID: 11044887.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Adam I-123 305352-16-3 Adam I 123 Adam I123 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.