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AZD8926

Catalog No. T30266 CAS 933785-68-3

Synonyms: AZD-8926, AZD 8926

AZD8926 is a potent and selective inhibitor of GSK3β(glycogen synthase kinase-3β). AZD8926 is potential for treating Alzheimer’s disease (AD), schizophrenia, and chronic as well as acute neurodegenerative diseases.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

AZD8926, CAS 933785-68-3

Pack Size	Availability	Price/USD
5 mg	8-10 weeks	$ 1,270.00 $ 1,016.00
50 mg	8-10 weeks	$ 2,580.00 $ 2,064.00
100 mg	8-10 weeks	$ 3,400.00 $ 2,720.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	AZD-8926, AZD 8926
Molecular Weight	533.52
Formula	C25H27F4N7O2
CAS No.	933785-68-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. A Novel Scalable Process to the GSK3β Inhibitor AZD8926 Based on a Heterocyclic Ziegler Coupling By Witt, Anette; Teodorovic, Peter; Linderberg, Mats; Johansson, Peter; Minidis, Anna From Organic Process Research & Development (2013), 17(4), 672-678. | Language: English, Database: CAPLUS 2. A new combination of (a) an α-4-β-2-neuronal nicotinic agonist and (b) a glycogen synthase kinase 3 (GSK3) inhibitor By Basun, Hans; Cox, Graham; Nordgren, Ingrid; Bencherif, Merouane From PCT Int. Appl. (2009), WO 2009017455 A1 20090205. | Language: English, Database: CAPLUS 3. New therapeutic combination of an antipsychotic and a glycogen synthase kinase 3 (GSK3) inhibitor 958 By Basun, Hans; Cox, Graham; Nordgren, Ingrid From PCT Int. Appl. (2009), WO 2009017453 A1 20090205. | Language: English, Database: CAPLUS 4. New therapeutic combination of a glycogen synthase kinase-3 (GSK3) inhibitor and an α7-nicotinic agonist By Basun, Hans; Cox, Graham; Nordgren, Ingrid rom PCT Int. Appl. (2009), WO 2009017454 A1 20090205. | Language: English, Database: CAPLUS

Dose Conversion

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Molecular Weight Calculator

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
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The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

AZD8926 933785-68-3 AZD-8926 AZD 8926 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.