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4-Methylumbelliferyl-α-D-Galactopyranoside

Name: 4-Methylumbelliferyl-α-D-Galactopyranoside
Brand: TargetMol
SKU: T37192
Price: 68 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T37192Cas No. 38597-12-5

Alias 4MU-α-Gal

4-Methylumbelliferyl-α-D-Galactopyranoside (4MU-α-Gal) (4-MU-α-Gal) is a fluorogenic substrate of α-galactosidase. In addition to its use in characterizing novel α-galactosidases, 4-MU-α-Gal is used in assays to evaluate deficiency in α-galactosidase activity related to Fabry disease.

4-Methylumbelliferyl-α-D-Galactopyranoside

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Purity: 99.28%

Catalog No. T37192Alias 4MU-α-GalCas No. 38597-12-5

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$68	In Stock	In Stock
100 mg	$108	In Stock	In Stock
200 mg	$175	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.28%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	4-Methylumbelliferyl-α-D-Galactopyranoside (4MU-α-Gal) (4-MU-α-Gal) is a fluorogenic substrate of α-galactosidase. In addition to its use in characterizing novel α-galactosidases, 4-MU-α-Gal is used in assays to evaluate deficiency in α-galactosidase activity related to Fabry disease.
In vitro	Hydrolysis of 4-MU-α-Gal releases the fluorescent product 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively[1].
Synonyms	4MU-α-Gal

Chemical Properties

Molecular Weight	338.31
Formula	C₁₆H₁₈O₈
Cas No.	38597-12-5
Smiles	Cc1cc(=O)oc2cc(O[C@H]3OC(CO)[C@H](O)[C@@H](O)C3O)ccc12

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMF: 45 mg/mL (133.01 mM), Sonication is recommended.

DMSO: 1 mg/mL (2.96 mM), Sonication is recommended.

Solution Preparation Table

DMSO/DMF

	1mg	5mg	10mg	50mg
1 mM	2.9559 mL	14.7793 mL	29.5587 mL	147.7934 mL

DMF

	1mg	5mg	10mg	50mg
5 mM	0.5912 mL	2.9559 mL	5.9117 mL	29.5587 mL
10 mM	0.2956 mL	1.4779 mL	2.9559 mL	14.7793 mL
20 mM	0.1478 mL	0.7390 mL	1.4779 mL	7.3897 mL
50 mM	0.0591 mL	0.2956 mL	0.5912 mL	2.9559 mL
100 mM	0.0296 mL	0.1478 mL	0.2956 mL	1.4779 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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