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RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His)
(Synonyms: Tumor necrosis factor ligand superfamily member 11, Tnfsf11, TNF-related activation-induced cytokine, Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, Osteoclast differentiation factor) Copy Product InfoSynonyms: Tumor necrosis factor ligand superfamily member 11, Tnfsf11, TNF-related activation-induced cytokine, Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, Osteoclast differentiation factor
Catalog No. TMPJ-01472 Copy Product Info
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 23-29 KDa and the accession number is O35235-1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $157 | - | In Stock | |
| 10 µg | $260 | 7-10 days | 7-10 days | |
| 20 µg | $445 | 7-10 days | 7-10 days | |
| 50 µg | $913 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:SDS-PAGE: 96%; SEC-HPLC: 100%
Color:Transparent
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Validated for osteoclast differentiation in mouse primary BMDMs at 125 ng/mL. BMDM cells are recommended, as RAW 264.7 cells often show inconsistent differentiation outcomes. |
| Description | RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 23-29 KDa and the accession number is O35235-1. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | N-6xHis-Flag |
| Accession Number | O35235-1 |
| Amino Acid | Lys158-Asp316 |
| Construction | Lys158-Asp316 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified)  |
| Endotoxin | < 0.01 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM His-HCl, 100 mM NaCl, 10% Trehalose, 0.05% Tween 80, pH5.5. |
| Synonyms | Tumor necrosis factor ligand superfamily member 11, Tnfsf11, TNF-related activation-induced cytokine, Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, Osteoclast differentiation factor |
| Research Background | Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thymus and lymph nodes. This cytokine can bind to TNFRSF11B/OPG andTNFRSF11A/RANK. Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption in humoral hypercalcemia of malignancy. It augments the ability of dendritic cells to stimulate naive T-cell proliferation. |
| Molecular Weight | 23-29 KDa (reducing condition) |
| Relative Density. | no data available |
| Shipping | Proteins are shipped with blue ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His) chemical structure | RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His) molecular weight
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