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Polysorbate 20

Catalog No. T9526 CAS 9005-64-5

Synonyms: Tween-20

Polysorbate 20 (Tween-20) ,sorbitan mono-9-octadecanoate poly(oxy-1,2-ethanediyl) derivatives, is used in the formulation of biotherapeutic products for both preventing surface adsorption and as a stabilizer against protein aggregation.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Polysorbate 20, CAS 9005-64-5

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100 mL	In stock	$ 57.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Tween-20
Molecular Weight	avg. 1228.0
Formula	C26H50O10
CAS No.	9005-64-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 100 mg/mL

References and Literature

1. Kerwin BA. Polysorbates 20 and 80 used in the formulation of protein biotherapeutics:structure and degradation pathways. J Pharm Sci. 2008 Aug;97(8):2924-35. 2. Hofer S, Stonig M, Wally V, Hartmann A, Fuchs D, Hermann M, Paparella M, Ganzera M, Gostner JM. Contradictory effects of chemical filters in UV/ROS- stressed human keratinocyte and fibroblast cells. ALTEX. 2019;36(2):231-244. 3. Diffey B. New Sunscreens and the Precautionary Principle. JAMA Dermatol. 2016 May 1;152(5):511-2.

Related compound libraries

This product is contained In the following compound libraries：

Human Metabolite Library Inactive Ingredient Library

Dose Conversion

You can also refer to dose conversion for different animals. More

In vivo Formulation Calculator (Clear solution)

Step One: Enter information below

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Average weight of animals

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Step Two: Enter the in vivo formulation

% DMSO+

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% Tween 80+

% ddH₂O

%DMSO+

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Molarity Calculator

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Molecular Weight Calculator

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Mass of a compound required to prepare a solution of known volume and concentration
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Concentration of a solution resulting from a known mass of compound in a specific volume

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
Press calculate
The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

See Example

An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
Press calculate
The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:
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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Polysorbate 20 9005-64-5 Others Tween-20 Polysorbate-20 Inhibitor Polysorbate20 inhibit inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.