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Pimozide-d4

Catalog No. T12476 CAS 1803193-57-8

Synonyms: Pimozide D4, R6238 D4

Pimozide D4 is a deuterium labeled Pimozide.

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Pimozide-d4, CAS 1803193-57-8

Pack Size	Availability	Price/USD	Quantity
1 mg	35 days	$ 1,210.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	Pimozide D4 is a deuterium labeled Pimozide.
Targets&IC50	STAT3:, α1-adrenoceptor:39 nM (ki), D2 receptor:1.4 nM (ki), Opamine D1 receptor:588 nM (ki), STAT5:, Opamine D3 receptor:2.5 nM (ki)

Synonyms	Pimozide D4, R6238 D4
Molecular Weight	465.57
Formula	C28H29F2N3O
CAS No.	1803193-57-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Ybema CE, et al. Adrenoceptors and dopamine receptors are not involved in the discriminative stimulus effect of the 5-HT1A receptor agonist flesinoxan. Eur J Pharmacol. 1994 Apr 21;256(2):141-7. 2. Cai N, et al. The STAT3 inhibitor pimozide impedes cell proliferation and induces ROS generation in human osteosarcoma by suppressing catalase expression. Am J Transl Res. 2017 Aug 15;9(8):3853-3866. eCollection 2017. 3. Erik A. Nelson, et al. The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors. Blood. 2011 Mar 24; 117(12): 3421-3429.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Pimozide-d4 1803193-57-8 GPCR/G Protein Neuroscience Dopamine Receptor Pimozide D4 Pimozide-d-4 Pimozided4 R6238 D4 inhibitor inhibit

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