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Leucyl-leucyl-leucine

Catalog No. T20433 CAS 10329-75-6

Synonyms: Trileucine

Leucyl-leucyl-leucine is may be used for pH-dependent endosomal membrane disruption to release agents. Trileucine is used to evaluate the absorption characteristics of reversed phase liquid chromatography (HPLC) media.

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Leucyl-leucyl-leucine Chemical Structure

Leucyl-leucyl-leucine, CAS 10329-75-6

Pack Size	Availability	Price/USD	Quantity
500 mg	5 days	$ 337.00
1 g	5 days	$ 544.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Trileucine
Molecular Weight	357.49
Formula	C18H35N3O4
CAS No.	10329-75-6

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Soluble

References and Literature

1. Go K, Parthasarathy R. Crystal structure and a twisted beta-sheet conformation of the tripeptide L-leucyl-L-leucyl-L-leucine monohydrate trimethanol solvate: conformation analysis of tripeptides. Biopolymers. 1995 Nov;36(5):607-14. PubMed PMID: 7578952. 2. Strauch KL, Carter TH, Miller CG. Overproduction of Salmonella typhimurium peptidase T. J Bacteriol. 1983 Nov;156(2):743-51. PubMed PMID: 6313618; PubMed Central PMCID: PMC217891. 3. Felsenberg J, Dyck Y, Kloß A, Dahlmann B, Kloetzel PM, Eisenhardt D. Two inhibitors of the ubiquitin proteasome system enhance long-term memory formation upon olfactory conditioning in the honeybee (Apis mellifera). J Exp Biol. 2014 Oct 1;217(Pt 19):3441-6. doi: 10.1242/jeb.108142. Epub 2014 Jul 25. PubMed PMID: 25063852. 4. Ding H, Portilla-Arias J, Patil R, Black KL, Ljubimova JY, Holler E. Distinct mechanisms of membrane permeation induced by two polymalic acid copolymers. Biomaterials. 2013 Jan;34(1):217-25. doi: 10.1016/j.biomaterials.2012.08.016. Epub 2012 Oct 9. PubMed PMID: 23063368; PubMed Central PMCID: PMC3487713.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Leucyl-leucyl-leucine 10329-75-6 Trileucine Leucyl leucyl leucine Leucylleucylleucine inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.