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Aluminum Hydroxide

Catalog No. T13545   CAS 21645-51-2

Aluminum Hydroxide is an orally active main form of aluminum used as an adjuvant. Aluminum hydroxide-based adjuvant researches including the repository effect, pro-phagocytic effect, and activation of the pro-inflammatory NLRP3 pathway.

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Aluminum Hydroxide Chemical Structure
Aluminum Hydroxide, CAS 21645-51-2
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1 g In stock $ 47.00
1 mL * 10 mM (in DMSO) In stock $ 50.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Aluminum Hydroxide is an orally active main form of aluminum used as an adjuvant. Aluminum hydroxide-based adjuvant researches including the repository effect, pro-phagocytic effect, and activation of the pro-inflammatory NLRP3 pathway.
In vivo Administered orally at a dosage of 100 mg/kg/day for a duration of seven days, Aluminum Hydroxide enhances lipid peroxidation while simultaneously reducing the activity of Superoxide Dismutase (SOD) in the brain. Additionally, it is capable of dissolving in distilled water to form a homogeneous suspension [3].
Molecular Weight 78
Formula AlH3O3
CAS No. 21645-51-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 1 mg/mL (12.82 mM), Sonication is recommended.

TargetMolReferences and Literature

1. He P, et al. Advances in aluminum hydroxide-based adjuvant research and its mechanism. Hum Vaccin Immunother. 2015;11(2):477-88. 2. Amini Y, et al. Aluminum hydroxide nanoparticles show strong activity to stimulate Th-1 immune response against tuberculosis. Artif Cells Nanomed Biotechnol. 2017 Nov;45(7):1331-1335. 3. Ohtawa M, et al. Effect of aluminum ingestion on lipid peroxidation in rats. Chem Pharm Bull (Tokyo). 1983 Apr;31(4):1415-8.

Related compound libraries

This product is contained In the following compound libraries:
Drug Repurposing Compound Library Bioactive Compound Library Inactive Ingredient Library Bioactive Compounds Library Max Anti-Metabolism Disease Compound Library FDA-Approved Drug Library FDA-Approved & Pharmacopeia Drug Library Anti-Diabetic Compound Library NO PAINS Compound Library Clinical Compound Library

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