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AV-105

Name: AV-105
Brand: TargetMol
SKU: T30216
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T30216Cas No. 1205550-99-7

Alias AV105, AV 105

AV-105 is a precursor for the synthesis of florbetapir-F18 (Amyvid). Amyvid is a positron emission tomography (PET) imaging agent targeting Aβ plaques, used for the diagnosis of Alzheimer's disease.

AV-105

🥰Excellent

Purity: 99.76%

Catalog No. T30216Alias AV105, AV 105Cas No. 1205550-99-7

AV-105 is a precursor for the synthesis of florbetapir-F18 (Amyvid). Amyvid is a positron emission tomography (PET) imaging agent targeting Aβ plaques, used for the diagnosis of Alzheimer's disease.

Pack Size	Price	Availability
5 mg	$35	In Stock
10 mg	$58	In Stock
25 mg	$105	In Stock
50 mg	$168	In Stock
100 mg	$268	In Stock
200 mg	$393	In Stock
1 mL x 10 mM (in DMSO)	$48	In Stock

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Batch Information

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Purity:99.76%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	AV-105 is a precursor for the synthesis of florbetapir-F18 (Amyvid). Amyvid is a positron emission tomography (PET) imaging agent targeting Aβ plaques, used for the diagnosis of Alzheimer's disease.
Synonyms	AV105, AV 105

Chemical Properties

Molecular Weight	612.73
Formula	C₃₂H₄₀N₂O₈S
Cas No.	1205550-99-7
Smiles	S(OCCOCCOCCOC1=CC=C(/C=C/C2=CC=C(N(C(OC(C)(C)C)=O)C)C=C2)C=N1)(=O)(=O)C3=CC=C(C)C=C3
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (81.6 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6320 mL	8.1602 mL	16.3204 mL	81.6020 mL
5 mM	0.3264 mL	1.6320 mL	3.2641 mL	16.3204 mL
10 mM	0.1632 mL	0.8160 mL	1.6320 mL	8.1602 mL
20 mM	0.0816 mL	0.4080 mL	0.8160 mL	4.0801 mL
50 mM	0.0326 mL	0.1632 mL	0.3264 mL	1.6320 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

AV-105