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(1S,4R)-N-Desmethyl Sertraline Hydrochloride

🥰Excellent
Catalog No. T9395Cas No. 675126-07-5

(1S,4R)-N-DesmethylSertralineHydrochloride is a Serotonin transporter and Norepinephrine transporter inhibitor with IC50 of 19 nM and 35 nM, respectively.

(1S,4R)-N-Desmethyl Sertraline Hydrochloride
Other Forms of (1S,4R)-N-Desmethyl Sertraline Hydrochloride:
(1R,4R)-N-desmethyl Sertraline hydrochlorideT84956675126-09-7
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(1S,4R)-N-Desmethyl Sertraline Hydrochloride

🥰Excellent
Purity: 99.71%
Catalog No. T9395Cas No. 675126-07-5
(1S,4R)-N-DesmethylSertralineHydrochloride is a Serotonin transporter and Norepinephrine transporter inhibitor with IC50 of 19 nM and 35 nM, respectively.
Pack SizePriceAvailabilityQuantity
1 mg$118In Stock
5 mg$280In Stock
10 mg$410In Stock
25 mg$642In Stock
50 mg$870In Stock
100 mg$1,170In Stock
200 mg$1,570In Stock
1 mL x 10 mM (in DMSO)$275In Stock
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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:99.71%
ee:100%
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COA CSFC LCMS HNMR

Product Introduction

Bioactivity
Description
(1S,4R)-N-DesmethylSertralineHydrochloride is a Serotonin transporter and Norepinephrine transporter inhibitor with IC50 of 19 nM and 35 nM, respectively.
Chemical Properties
Molecular Weight328.66
FormulaC16H16Cl3N
Cas No.675126-07-5
Smiles[H]Cl.N[C@@H]1CC[C@@H](C2=CC=C(Cl)C(Cl)=C2)C3=C1C=CC=C3
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (182.56 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0427 mL15.2133 mL30.4266 mL152.1329 mL
5 mM0.6085 mL3.0427 mL6.0853 mL30.4266 mL
10 mM0.3043 mL1.5213 mL3.0427 mL15.2133 mL
20 mM0.1521 mL0.7607 mL1.5213 mL7.6066 mL
50 mM0.0609 mL0.3043 mL0.6085 mL3.0427 mL
100 mM0.0304 mL0.1521 mL0.3043 mL1.5213 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

N-Desmethyl Sertraline Hydrochloride(1S,4R)NDesmethyl Sertraline Hydrochloride(1S,4R) N Desmethyl Sertraline Hydrochloride
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