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TargetMol | Compound Library

Glycometabolism Compound Library

Catalog No. L2520

Glucose and glycogen are initial materials involved in the glycometabolism. A chronically irregular diet could result in the disorders of glycometabolism, which was manifested by the gradual deterioration of glucose tolerance over time, leading to the increased fasting blood glucose or impaired glucose tolerance. The clinical manifestations of glycometabolism-related disorder are hyperglycemia or hypoglycemia, which might eventually contribute to some serious diseases, such as diabetes, G6PD deficiency, obesity and malnutrition. In addition, favored glycolysis under aerobic conditions (aerobic glycolysis), or the Warburg effect, the transition from oxidative phosphorylation to glycolysis, accompanied by the accumulation of lactate by-products in the surrounding microenvironment and 20-30 times faster rate of glucose metabolism than the complete oxidation of glucose in the mitochondria, represents the most typical change observed in the metabolism of cancer cells. Therefore, a key to selective killing of cancer cells lies in their dependence on glycolysis. Targeting tumor cell metabolism has become a successful approach to the prevention or treatment of cancer. Most efforts have focused on the use of small molecules to inhibit the function of metabolic enzymes, which has been comprehensively reviewed elsewhere. Increasing evidence supports many glycolytic enzymes and transporters as candidates for cancer treatment. TargetMol’s Glycometabolism Compound Library collects 1196 glycometabolism-related compounds, targeting GLUTs, Hexokinase(HK), Pyruvate Kinase(PK ), phosphofructokinase(PFK), IDH1/2, LDH, AMPK, etc. It is a powerful tool for research in glycometabolism-related disorders and cancer.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2520

Glycometabolism Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • 1196 glycometabolism-related comounds, can be used for HTS and HCT;
  • Targets contain GLUTs、Hexokinase(HK)、Pyruvate Kinase(PK)、phosphofructokinase(PFK)、IDH1/2、LDH、AMPK, etc.;
  • Detailed compound information with structure, target, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.
  • All compounds are in stock.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

PI3K
Apoptosis
Autophagy
PPAR
Phosphatase
GSK-3
mTOR
Mitochondrial Metabolism
AMPK
Carbonic Anhydrase
HIF/HIF Prolyl-Hydroxylase
p53
HIF
CDK
IGF-1R
Akt
DNA-PK
Glucokinase
Dehydrogenase
DPP-4
S6 Kinase
PDK
Proteasome
Ferroptosis
Reductase
SGLT
ATM/ATR
Glucocorticoid Receptor
Src
COX
Mdm2
Parasite
Glucosidase
Antibacterial
transporter
NAMPT
Isocitrate Dehydrogenase (IDH)
Antibiotic
VEGFR
Potassium Channel
Calcium Channel
PKC
Reactive Oxygen Species
SGK
NADPH
FLT
PKM
Mitophagy
PKA
Wnt/beta-catenin
PDE
Chk
Aurora Kinase
PI4K
P450
ROCK
Casein Kinase
Endogenous Metabolite
ATPase
HIV Protease
Antifungal
Bcr-Abl
DNA/RNA Synthesis
NF-κB
FGFR
Microtubule Associated
FAK
PERK
TRP/TRPV Channel
SIK
ROS
PDGFR
EGFR
ALK
Influenza Virus
IκB/IKK
NADPH-oxidase
c-Met/HGFR
Antioxidant
DYRK
Virus Protease
ERK
Adrenergic Receptor
E1/E2/E3 Enzyme
Hexokinase
HSV
IL Receptor
MMP
Androgen Receptor
Interleukin
MAPK
Prostaglandin Receptor
STAT
HDAC
Syk
Sodium Channel
Tyrosinase
Chloride channel
Transferase
Histone Methyltransferase
ADC Cytotoxin
p38 MAPK
Estrogen/progestogen Receptor
IFNAR
JNK
Tyrosine Kinases
Serine Protease
Aryl Hydrocarbon Receptor
Gamma-secretase
Raf
Phosphorylase
DNA Alkylation
PGC-1α
Epigenetic Reader Domain
TGF-beta/Smad
OXPHOS
HSP
Trk receptor
Sirtuin
Nrf2
MELK
Beta Amyloid
c-Fms
GPR
Hydroxylase
PLK
c-RET
MEK
Cannabinoid Receptor
DNA Methyltransferase
Proton pump
NOS
Monocarboxylate transporter
Dopamine Receptor
YAP
DNA Alkylator/Crosslinker
Adenosine Receptor
BACE
Histone Demethylase
RAAS
Tie-2
GTPase
Progesterone Receptor
ABC
HBV
PARP
Pim
Rho
Serine/threonin kinase
Cysteine Protease
Leukotriene Receptor
PYK2
Caspase
Glutaminase
MAO
CSF-1R
Immunology/Inflammation related
iGluR
Myosin
FLAP
Drug Metabolite
Guanylate cyclase
BCL
Fatty Acid Synthase
PAK
JAK
PTEN
Epoxide Hydrolase
cAMP
GluR
Lipoxygenase
CaMK
DUB
ATP Citrate Lyase
Lipid
Beta-Secretase
AChE
Acyltransferase
P-gp
STING
LRRK2
Free radical scavengers
AIM2
CPT
Reverse Transcriptase
Ligand for E3 Ligase
Phospholipase
GABA Receptor
TNF
AChR
DAPK
Anti-infection
c-Kit
cholecystokinin
Thrombin
AhR
NOD-like Receptor (NLR)
CFTR
MLK
S1P Receptor