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Rabbit Anti-Human IgG1-Fc Secondary Antibody (5D608)

😃Good
Catalog No. TMAY-00003
Alias Ighg1, IgG1 Fc

Rabbit Anti-Human IgG1-Fc Secondary Antibody (5D608) is a Rabbit antibody targeting IgG1 Fc. Rabbit Anti-Human IgG1-Fc Secondary Antibody (5D608) can be used in ELISA.

Rabbit Anti-Human IgG1-Fc Secondary Antibody (5D608)

Rabbit Anti-Human IgG1-Fc Secondary Antibody (5D608)

😃Good
Catalog No. TMAY-00003Alias Ighg1, IgG1 Fc
Rabbit Anti-Human IgG1-Fc Secondary Antibody (5D608) is a Rabbit antibody targeting IgG1 Fc. Rabbit Anti-Human IgG1-Fc Secondary Antibody (5D608) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
20 μL$92 7-10 days
100 μL$270 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Rabbit Monoclonal

Application: ELISA

Reactivity: Human
AliasIghg1, IgG1 Fc
Ig Type
Rabbit IgG
Clone
5D608
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human IgG1-Fc.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundAs a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetramer contains two heavy chains (5 kDa ) and two light chains (25 kDa) linked by disulfide bonds, that is the two identical halves form the Y-like shape. IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment ("crystallizable" fragment). IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR ) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues. Protein G or Protein A on the surface of certain Staphylococcal and Streptococcal strains specifically binds with the Fc region of IgGs, and has numerous applications in biotechnology as a reagent for affinity purification. Recombinant IgG Fc Region is suggested to represent a potential anti-inflammatory drug for treatment of human autoimmune diseases.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human IgG1-Fc Protein
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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