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Murine ZP3 peptide (330-342)

Name: Murine ZP3 peptide (330-342)
Brand: TargetMol
SKU: TP4480
Rating: 4.5 (1 reviews)

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Murine ZP3 peptide (330-342) is a fragment of the zona pellucida 3 polypeptide with the amino acid sequence NSSSSQFQIHGPR. It has the capability to induce autoimmune premature ovarian failure (POF) and is useful in research related to ovarian failure.

Murine ZP3 peptide
(330-342)

Cas No. 152439-29-7

Pack Size	Price	USA Stock	Global Stock	Quantity
10 mg	Inquiry	Inquiry	Inquiry
50 mg	Inquiry	Inquiry	Inquiry

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description

In vivo

Murine ZP3 peptide (330-342), emulsified with complete Freund's adjuvant (CFA) at a concentration of 50 nmol/L, is administered subcutaneously to female Balb/c mice, with a second injection 7 days later using incomplete Freund's adjuvant (IFA). This treatment reliably induces ovarian failure, as evidenced by disrupted serum hormone and cytokine profiles, altered ovarian and uterine morphology, reduced expression of endometrial receptivity markers, and local immune cell population disturbances.

Chemical Properties

Molecular Weight	1444.51
Formula	C₆₀H₉₃N₂₁O₂₁
Cas No.	152439-29-7
Smiles	C(N[C@@H](CCCNC(=N)N)C(O)=O)(=O)[C@H]1N(C(CNC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(N)=O)N)=O)CO)=O)CO)=O)CO)=O)CO)=O)CCC(N)=O)=O)=O)CCC(N)=O)=O)[C@H](CC)C)=O)=O)=O)CCC1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Related Tags: Murine ZP3 peptide (330-342) in vivo | Murine ZP3 peptide (330-342) formula | Murine ZP3 peptide (330-342) molecular weight