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Tolperisone free base

Catalog No. T21077 CAS 728-88-1

Synonyms: Mydeton, Atmosgen free base, Mideton, Menopatol, Besnoline free base, Mydocalm

Tolperisone free base, a centrally acting muscle relaxant, has been used for the symptomatic treatment of spasticity and muscle spasm.

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Tolperisone free base Chemical Structure

Tolperisone free base, CAS 728-88-1

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Tolperisone free base, a centrally acting muscle relaxant, has been used for the symptomatic treatment of spasticity and muscle spasm.

Synonyms	Mydeton, Atmosgen free base, Mideton, Menopatol, Besnoline free base, Mydocalm
Molecular Weight	245.36
Formula	C16H23NO
CAS No.	728-88-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Soluble

References and Literature

1. Luo D, Wu G, Ji Y, Zhang Z, He F, Mou X, Zhu Q, Yang B. The comparative study of clinical efficacy and safety of baclofen vs tolperisone in spasticity caused by spinal cord injury. Saudi Pharm J. 2017 May;25(4):655-659. doi: 10.1016/j.jsps.2017.04.041. Epub 2017 May 7. PubMed PMID: 28579907; PubMed Central PMCID: PMC5447437. 2. Agarwal S, Patel T, Shah N, Patel BM. Comparative study of therapeutic response to baclofen vs tolperisone in spasticity. Biomed Pharmacother. 2017 Mar;87:628-635. doi: 10.1016/j.biopha.2017.01.005. Epub 2017 Jan 10. Erratum in: Biomed Pharmacother. 2017 Aug;92:1140. PubMed PMID: 28086137. 3. Tekes K. Basic aspects of the pharmacodynamics of tolperisone, a widely applicable centrally acting muscle relaxant. Open Med Chem J. 2014 Jul 11;8:17-22. doi: 10.2174/1874104501408010017. eCollection 2014. PubMed PMID: 25132868; PubMed Central PMCID: PMC4133921.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Tolperisone free base 728-88-1 Atmosgen Mydeton Tolperisone Atmosgen free base Besnoline Mideton Menopatol Besnoline free base Mydocalm inhibitor inhibit

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