Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate, combines a Thalidomide-based cereblon ligand with a two-unit PEG linker for use in PROTAC technology[1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 84.00 | |
5 mg | 5 days | $ 137.00 | |
10 mg | 5 days | $ 196.00 |
Description | Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate, combines a Thalidomide-based cereblon ligand with a two-unit PEG linker for use in PROTAC technology[1]. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
Synonyms | Thalidomide-NH-PEG2-C2-NH2 hydrochloride |
Molecular Weight | 440.88 |
Formula | C19H25ClN4O6 |
CAS No. | 2245697-87-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Thalidomide-PEG2-C2-NH2 hydrochloride 2245697-87-2 Others Thalidomide-PEG-2-C2-NH2 hydrochloride ThalidomidePEG2C2NH2 hydrochloride Thalidomide PEG2 C2 NH2 hydrochloride Thalidomide-NH-PEG2-C2-NH2 hydrochloride Thalidomide-PEG2-C2-NH2 Hydrochloride Thalidomide-NH-PEG2-C2-NH2 Hydrochloride inhibitor inhibit