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N6-Succinyllysine

Catalog No. T33564 CAS 52685-16-2

Synonyms: Succinyllysine, 6-, epsilon-Succinyllysine

N6-Succinyllysine is a bioactive chemical.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

N6-Succinyllysine, CAS 52685-16-2

Pack Size	Availability	Price/USD	Quantity
5 mg	5 days	$ 970.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

N6-Succinyllysine is a bioactive chemical.

Synonyms	Succinyllysine, 6-, epsilon-Succinyllysine
Molecular Weight	246.26
Formula	C10H18N2O5
CAS No.	52685-16-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Zhang Z, Tan M, Xie Z, Dai L, Chen Y, Zhao Y. Identification of lysine succinylation as a new post-translational modification. Nat Chem Biol. 2011 Jan;7(1):58-63. doi: 10.1038/nchembio.495. Epub 2010 Dec 12. PubMed PMID: 21151122; PubMed Central PMCID: PMC3065206. 2. Kumar S, Lombard DB. Mitochondrial sirtuins and their relationships with metabolic disease and cancer. Antioxid Redox Signal. 2015 Apr 20;22(12):1060-77. doi: 10.1089/ars.2014.6213. Epub 2015 Feb 10. Review. PubMed PMID: 25545135; PubMed Central PMCID: PMC4389911. 3. He D, Wang Q, Li M, Damaris RN, Yi X, Cheng Z, Yang P. Global Proteome Analyses of Lysine Acetylation and Succinylation Reveal the Widespread Involvement of both Modification in Metabolism in the Embryo of Germinating Rice Seed. J Proteome Res. 2016 Mar 4;15(3):879-90. doi: 10.1021/acs.jproteome.5b00805. Epub 2016 Jan 28. PubMed PMID: 26767346. 4. Colak G, Xie Z, Zhu AY, Dai L, Lu Z, Zhang Y, Wan X, Chen Y, Cha YH, Lin H, Zhao Y, Tan M. Identification of lysine succinylation substrates and the succinylation regulatory enzyme CobB in Escherichia coli. Mol Cell Proteomics. 2013 Dec;12(12):3509-20. doi: 10.1074/mcp.M113.031567. Epub 2013 Oct 31. PubMed PMID: 24176774; PubMed Central PMCID: PMC3861704.

Dose Conversion

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

N6-Succinyllysine 52685-16-2 Succinyllysine, 6- epsilon-Succinyllysine N-6-Succinyllysine N6Succinyllysine N6 Succinyllysine inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.