Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Luteolin-7-rutinoside has both antifungal activities and anti-arthritic, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 188.00 | |
5 mg | 35 days | $ 597.00 | |
10 mg | 35 days | $ 1,120.00 | |
25 mg | 35 days | $ 2,340.00 |
Description | Luteolin-7-rutinoside has both antifungal activities and anti-arthritic, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection. |
In vitro | Luteolin-7-rutinoside demonstrates dose-dependent immunomodulatory effects in T cells and macrophages. At concentrations of 40 μg/mL, it induces T cell proliferation at a rate comparable to that seen with 20 μg/mL, indicating a potential plateau in efficacy with increased dosage. A lower dose of 10 μg/mL (referred to as lonicerin) significantly reduces T cell proliferation by approximately 47% relative to control groups treated with Luteolin-7-rutinoside (p<0.05), highlighting its suppressive capability. Additionally, Luteolin-7-rutinoside shifts the Th1-Th2 balance towards Th2-type responses and inhibits nitric oxide (NO) production from macrophages, further evidencing its immunological influence. |
Molecular Weight | 594.52 |
Formula | C27H30O15 |
CAS No. | 20633-84-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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