Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Apaziquone has potential antineoplastic and radiosensitization activities. It is converted to active metabolites in hypoxic cells by intracellular reductases, which are present in greater amounts in hypoxic tumor cells. The active metabolites alkylate DNA, resulting in apoptotic cell death.
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Description | Apaziquone has potential antineoplastic and radiosensitization activities. It is converted to active metabolites in hypoxic cells by intracellular reductases, which are present in greater amounts in hypoxic tumor cells. The active metabolites alkylate DNA, resulting in apoptotic cell death. |
Synonyms | EO-9, NSC382459, EO9, NSC 382459, EO 9, NSC-382459 |
Molecular Weight | 288.3 |
Formula | C15H16N2O4 |
CAS No. | 114560-48-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
H2O: Insoluble
You can also refer to dose conversion for different animals. More
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Apaziquone 114560-48-4 EO-9 NSC382459 EO9 NSC 382459 EO 9 NSC-382459 inhibitor inhibit