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Amidantel hydrochloride

Catalog No. T29979 CAS 69884-15-7

Synonyms: BAY-d 8815, BAY d 8815

Amidantel hydrochloride is a new aminophenylamidine with an interesting anthelminthic spectrum. In rodents the compound is active against nematodes, filariae and cestodes. Of special interest is the high efficacy in dogs against hookworms and large roundworms. Amidantel was well tolerated by all animals tested and did not show teratogenic effects.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Amidantel hydrochloride Chemical Structure

Amidantel hydrochloride, CAS 69884-15-7

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	BAY-d 8815, BAY d 8815
Molecular Weight	285.77
Formula	C13H20ClN3O2
CAS No.	69884-15-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Pejo E, Santer P, Jeffrey S, Gallin H, Husain SS, Raines DE. Analogues of etomidate: modifications around etomidate's chiral carbon and the impact on in vitro and in vivo pharmacology. Anesthesiology. 2014 Aug;121(2):290-301. doi: 10.1097/ALN.0000000000000268. PubMed PMID: 24777068; PubMed Central PMCID: PMC4121658. 2. Bruder EA, Ball IM, Ridi S, Pickett W, Hohl C. Single induction dose of etomidate versus other induction agents for endotracheal intubation in critically ill patients. Cochrane Database Syst Rev. 2015 Jan 8;1:CD010225. doi: 10.1002/14651858.CD010225.pub2. Review. PubMed PMID: 25568981. 3. Liu HC, Zhu D, Wang C, Guan H, Li S, Hu C, Chen Z, Hu Y, Lin H, Lian QQ, Ge RS. Effects of Etomidate on the Steroidogenesis of Rat Immature Leydig Cells. PLoS One. 2015 Nov 10;10(11):e0139311. doi: 10.1371/journal.pone.0139311. eCollection 2015. PubMed PMID: 26555702; PubMed Central PMCID: PMC4640886. 4. Liu S, Zhang XP, Han NN, Lv S, Xiong JY. Pretreatment with low dose etomidate prevents etomidate-induced rat adrenal insufficiency by regulating oxidative stress-related MAPKs and apoptosis. Environ Toxicol Pharmacol. 2015 May;39(3):1212-20. doi: 10.1016/j.etap.2015.04.014. Epub 2015 Apr 25. PubMed PMID: 25989534.

Dose Conversion

You can also refer to dose conversion for different animals. More

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Amidantel hydrochloride 69884-15-7 BAY-d 8815 Amidantel Hydrochloride BAY d 8815 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.