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3CLpro/3C-like Protease Protein (A191T), SARS-COV-2, Recombinant

Catalog No. TMPK-01343 Copy Product Info
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (A191T), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.8 kDa and the accession number is YP_009725301.1.

3CLpro/3C-like Protease Protein (A191T), SARS-COV-2, Recombinant

Catalog No. TMPK-01343
Copy Product Info

3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (A191T), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.8 kDa and the accession number is YP_009725301.1.

3CLpro/3C-like Protease Protein (A191T), SARS-COV-2, Recombinant
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$917-10 days7-10 days
10 μg$1487-10 days7-10 days
20 μg$2457-10 days7-10 days
50 μg$4837-10 days7-10 days
100 μg$8137-10 days7-10 days
200 μg$1,4707-10 days7-10 days
500 μg$3,2507-10 days7-10 days
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In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
For research use only—not for human use. No sales to individuals. Use as intended only.
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Biological Activity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (A191T), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.8 kDa and the accession number is YP_009725301.1.
Species
SARS-CoV-2
Expression System
E. coli
TagTag Free
Accession NumberYP_009725301.1
Synonyms
Mpro,M Proteinase,3CL-Mpro,3CL Protease
Construction
Ser1-Gln306(A191T)
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight33.8 kDa (predicted) same as Tris-Bis PAGE result.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in 25 mM HEPES, 2.5 mM DTT, 10% Glycerol (pH 7.5).
Stability & Storage
It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingProteins are shipped with blue ice.
Research Background
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase.

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