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(±)8,9-DiHETE

Name: (±)8,9-DiHETE
Brand: TargetMol
SKU: T37229
Rating: 4.5 (1 reviews)

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Catalog No. T37229Cas No. 867350-87-6

(±)8,9-DiHETE is a major metabolite of the 20:5 ω-3 fatty acid eicosapentaenoic acid .[1] It is produced in rat liver microsomes, but not renal microsomes, by the generation of the unstable intermediate 8,9-epoxy eicosatetraenoic acid from EPA by cytochrome P450 monooxygenases. Dietary EPA supplementation in humans results in substantial urinary excretion of vicinal diols, including 8,9, 11,12, and 14,15 forms.[2]

(±)8,9-DiHETE

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Catalog No. T37229Cas No. 867350-87-6

Pack Size	Price	USA Warehouse	Global Warehouse
25 μg	$378	35 days	35 days
50 μg	$693	35 days	35 days
100 μg	$1,330	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	336.472
Formula	C₂₀H₃₂O₄
Cas No.	867350-87-6
Smiles	CC\C=C/C\C=C/C\C=C/CC(O)C(O)C\C=C/CCCC(O)=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

PBS (pH 7.2): 0.5 mg/mL (1.49 mM), Sonication is recommended.

DMSO: 30 mg/mL (89.16 mM), Sonication is recommended.

Ethanol: 30 mg/mL (89.16 mM), Sonication is recommended.

DMF: 30 mg/mL (89.16 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH 7.2)/DMSO/Ethanol/DMF

	1mg	5mg	10mg	50mg
1 mM	2.9720 mL	14.8601 mL	29.7202 mL	148.6008 mL

DMSO/Ethanol/DMF

	1mg	5mg	10mg	50mg
5 mM	0.5944 mL	2.9720 mL	5.9440 mL	29.7202 mL
10 mM	0.2972 mL	1.4860 mL	2.9720 mL	14.8601 mL
20 mM	0.1486 mL	0.7430 mL	1.4860 mL	7.4300 mL
50 mM	0.0594 mL	0.2972 mL	0.5944 mL	2.9720 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

8,9-DiHETE(±)8,9DiHETE(±)8,9 DiHETE