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TargetMol | Compound Library

Stem Cell Differentiation Compound Library

Catalog No. L8000

Stem cells can differentiate into other types of cells and can divide to produce more of the same type of stem cells. For example, embryonic stem cells can differentiate into all the specialized cells—ectoderm, endoderm and mesoderm. Somatic stem cells are thought to be limited to differentiating into different cell types of their tissue of origin. To generate enough specialized cells or tissues that can be used for specific purposes such as tissue regeneration, cell-based therapies, drug screening, or disease models, scientists (must control the cell fate of pluripotent stem cells) are currently working on methods to effectively differentiate stem cells into functional specialized cells. Natural and synthetic small molecules have been shown to be useful chemical tools for controlling and manipulating the fates of cells. For example, Glycogen synthase kinase 3β (GSK-3β) inhibitor could induce differentiation of neural progenitor cells (NPCs). Bone marrow stromal stem cells (BMSSCs) may have potential to differentiate in vitro and in vivo into hepatocytes following the treatment of inhibitor of histone deacetylase and some well-defined cytokines.

Stem Cell Differential Compound Library from TargetMol, a unique collection of 1880 stem cell differentiation signaling targeted compounds, can be used for stem cell research and related drug screening (high throughput and high content screening).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L8000

Stem Cell Differentiation Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product Description Product Description

  • A unique collection of 1880 stem cell differentiation signaling targeted compounds for high throughput and high content screening;
  • Effective tool for research in regenerative medicine, stem cell differentiation signaling, and drug screening based on stem cells;
  • Targets include Wnt, GSK-2, Hedgehog, JAK, ROCK, γ-secretase, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
EGFR
Wnt/beta-catenin
STAT
PI3K
JAK
Ras
Akt
GSK-3
TGF-beta/Smad
NF-κB
p38 MAPK
mTOR
ERK
Antibacterial
CDK
Endogenous Metabolite
Casein Kinase
PPAR
ROCK
Gamma-secretase
Histone Methyltransferase
ROS
ALK
AMPK
Hedgehog/Smoothened
Kras
Interleukin
Potassium Channel
Src
PKC
Tyrosine Kinases
VEGFR
Caspase
COX
FLT
YAP
JNK
Parasite
Smo
Antibiotic
MDM-2/p53
PKA
TNF
IGF-1R
S6 Kinase
PARP
DNA/RNA Synthesis
HER
Raf
Beta Amyloid
Ferroptosis
Pim
DNA-PK
Bcl-2 Family
Aurora Kinase
MAPK
p53
Histone Demethylase
Reactive Oxygen Species
ATM/ATR
FGFR
MEK
Bcr-Abl
PDGFR
Epigenetic Reader Domain
NO Synthase
Antifungal
Calcium Channel
Mitophagy
Influenza Virus
HDAC
Cytochromes P450
HIV Protease
Rho
PDE
IL Receptor
Nrf2
5-HT Receptor
c-Kit
DNA Methyltransferase
Sodium Channel
Dehydrogenase
c-Met/HGFR
MMP
IκB/IKK
AChR
HIF/HIF Prolyl-Hydroxylase
Phosphatase
CXCR
Sirtuin
Histone Acetyltransferase
Adrenergic Receptor
E1/E2/E3 Enzyme
TLR
Virus Protease
HSV
Beta-Secretase
Porcupine
Mdm2
Antioxidant
DYRK
c-Myc
Serine/threonin kinase
Drug Metabolite
Lipoxygenase
PDK
Microtubule Associated
FAK
Estrogen Receptor/ERR
Serine Protease
RIP kinase
c-Fms
c-RET
ATPase
Estrogen/progestogen Receptor
BACE
Mitochondrial Metabolism
PTEN
Chk
Survivin
SARS-CoV
PI4K
Tyrosinase
Dopamine Receptor
Integrin
PERK
Histamine Receptor
Aryl Hydrocarbon Receptor
Topoisomerase
Cholinesterase (ChE)
CaMK
Hippo pathway
GABA Receptor
SGK
Syk
ROS Kinase
MLK
HCV Protease
GTPase
OCT
HBV
Glucocorticoid Receptor
Glucosidase
Molecular Glues
P-gp
HSP
Retinoid Receptor
Anti-infection
PD-1/PD-L1
Monoamine Oxidase
BTK
GPCR
NOS
Carbonic Anhydrase
Adenosine Receptor
IFNAR
LIM Kinase
TRP/TRPV Channel
SIK
Myosin
GRK
Antiviral
Prostaglandin Receptor
PLK
Proteasome
DNA Alkylator/Crosslinker
NADPH
Tie-2
MRP
Cholecystokinin Receptor
AAK1
FXR
RANKL/RANK
MAO
Fatty Acid Synthase
Cadherin
GluR
OXPHOS
LRRK2
Trk receptor
transporter
Pyroptosis
MELK
Phospholipase
HIF
DAPK
NADPH-oxidase
NOD-like Receptor (NLR)
IKZF
Proton pump
PROTACs
Adenylyl Cyclase
Transferase
Amino Acids and Derivatives
Na+/Ca2+ Exchanger
RAAS
Glutathione Peroxidase
Bcl-6
Serotonin Transporter
Nucleoside Antimetabolite/Analog
PYK2
CSF-1R
IAP
Immunology/Inflammation related
UGT
NMDAR
ABC Transporter
Antifection
Stearoyl-CoA Desaturase (SCD)
CCR
ACK1
Angiotensin-converting Enzyme (ACE)
cAMP
glycosidase
DUB
Lipid
BCRP
Acyltransferase
MNK
PAI-1
RSV
FKBP
KLF
CRISPR/Cas9
Cannabinoid Receptor
NOD
IRAK
Melanin-concentrating Hormone Receptor (MCHR)
Advanced Glycation End Products
Chloride channel
DHFR
MyD88
Y Box Binding Protein 1
Arginase
LPL Receptor
Reductase
Lipase
Necroptosis
gp120/CD4
VDA
Progesterone Receptor
CaSR
Photosensitizer
Cell Cycle Arrest
Cysteine Protease
Liver X Receptor
NAMPT
Stemness kinase
IDO
Prolyl Endopeptidase (PREP)
Annexin A
FABP
LDL
Phosphorylase
AAK1 (AP2 associated kinase 1)
P2X Receptor
Na-K-Cl cotransporter
Opioid Receptor
MAGL
DNA Alkylation
Bombesin Receptor
Epoxide Hydrolase
Thrombopoietin Receptor
Orphan Receptor
DNA
Indoleamine 2,3-Dioxygenase (IDO)
Androgen Receptor
ATP Citrate Lyase
Ephrin Receptor
hCE
Methionine Adenosyltransferase (MAT)
GST
Reverse Transcriptase
Aromatase
LPA Receptor
Aquaporin
Hydroxylase
FOXO
Cuproptosis
Discoidin Domain Receptor (DDR)
BMI-1
TAM Receptor
Sigma receptor
Protease-activated Receptor
AhR
Kinesin
PKM
S1P Receptor
Vitamin
PGC-1α