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TargetMol | Compound Library

Stem Cell Differentiation Compound Library

Catalog No. L8000

Stem cells can differentiate into other types of cells and can divide to produce more of the same type of stem cells. For example, embryonic stem cells can differentiate into all the specialized cells—ectoderm, endoderm and mesoderm. Somatic stem cells are thought to be limited to differentiating into different cell types of their tissue of origin. To generate enough specialized cells or tissues that can be used for specific purposes such as tissue regeneration, cell-based therapies, drug screening, or disease models, scientists (must control the cell fate of pluripotent stem cells) are currently working on methods to effectively differentiate stem cells into functional specialized cells. Natural and synthetic small molecules have been shown to be useful chemical tools for controlling and manipulating the fates of cells. For example, Glycogen synthase kinase 3β (GSK-3β) inhibitor could induce differentiation of neural progenitor cells (NPCs). Bone marrow stromal stem cells (BMSSCs) may have potential to differentiate in vitro and in vivo into hepatocytes following the treatment of inhibitor of histone deacetylase and some well-defined cytokines.

Stem Cell Differential Compound Library from TargetMol, a unique collection of 1880 stem cell differentiation signaling targeted compounds, can be used for stem cell research and related drug screening (high throughput and high content screening).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L8000

Stem Cell Differentiation Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product Description Product Description

  • A unique collection of 1880 stem cell differentiation signaling targeted compounds for high throughput and high content screening;
  • Effective tool for research in regenerative medicine, stem cell differentiation signaling, and drug screening based on stem cells;
  • Targets include Wnt, GSK-2, Hedgehog, JAK, ROCK, γ-secretase, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
EGFR
Wnt/beta-catenin
STAT
JAK
PI3K
Ras
Akt
GSK-3
TGF-beta/Smad
NF-κB
p38 MAPK
mTOR
ERK
Antibacterial
CDK
Endogenous Metabolite
Casein Kinase
PPAR
ROCK
Gamma-secretase
Histone Methyltransferase
ROS
ALK
AMPK
Hedgehog/Smoothened
Kras
Interleukin
Potassium Channel
Src
PKC
VEGFR
Tyrosine Kinases
Caspase
COX
FLT
Parasite
YAP
JNK
Antibiotic
Smo
MDM-2/p53
TNF
PKA
IGF-1R
S6 Kinase
PARP
HER
DNA/RNA Synthesis
Raf
Beta Amyloid
Ferroptosis
Pim
Bcl-2 Family
DNA-PK
MAPK
p53
Aurora Kinase
Reactive Oxygen Species
Histone Demethylase
FGFR
MEK
ATM/ATR
Antifungal
PDGFR
NO Synthase
Bcr-Abl
Epigenetic Reader Domain
Calcium Channel
HDAC
Influenza Virus
Mitophagy
Cytochromes P450
HIV Protease
Rho
Sodium Channel
IL Receptor
PDE
Nrf2
5-HT Receptor
c-Kit
c-Met/HGFR
MMP
HIF/HIF Prolyl-Hydroxylase
Dehydrogenase
DNA Methyltransferase
IκB/IKK
AChR
Histone Acetyltransferase
Sirtuin
Phosphatase
CXCR
E1/E2/E3 Enzyme
TLR
Adrenergic Receptor
HSV
Porcupine
Beta-Secretase
Mdm2
DYRK
c-Myc
Lipoxygenase
Antioxidant
Virus Protease
Serine/threonin kinase
Drug Metabolite
Microtubule Associated
FAK
PDK
Serine Protease
c-Fms
RIP kinase
Estrogen Receptor/ERR
c-RET
Mitochondrial Metabolism
Chk
PI4K
ATPase
PERK
PTEN
Tyrosinase
Estrogen/progestogen Receptor
Survivin
BACE
GABA Receptor
ROS Kinase
Syk
Cholinesterase (ChE)
Hippo pathway
Aryl Hydrocarbon Receptor
Topoisomerase
MLK
Dopamine Receptor
CaMK
SGK
Integrin
Histamine Receptor
SARS-CoV
GTPase
PD-1/PD-L1
HBV
HCV Protease
P-gp
Retinoid Receptor
OCT
Glucocorticoid Receptor
Molecular Glues
Anti-infection
Monoamine Oxidase
Glucosidase
HSP
BTK
GPCR
Adenosine Receptor
LIM Kinase
PLK
Carbonic Anhydrase
NOS
Prostaglandin Receptor
IFNAR
TRP/TRPV Channel
GRK
Antiviral
SIK
Myosin
MAO
MELK
HIF
Trk receptor
GluR
DNA Alkylator/Crosslinker
FXR
Cadherin
OXPHOS
LRRK2
Pyroptosis
NADPH-oxidase
MRP
Fatty Acid Synthase
DAPK
NADPH
RANKL/RANK
transporter
NOD-like Receptor (NLR)
Proteasome
Tie-2
Cholecystokinin Receptor
AAK1
Phospholipase
IKZF
Na+/Ca2+ Exchanger
cAMP
PAI-1
NOD
IRAK
Amino Acids and Derivatives
Immunology/Inflammation related
NMDAR
Angiotensin-converting Enzyme (ACE)
MNK
RSV
KLF
PROTACs
Nucleoside Antimetabolite/Analog
IAP
ABC Transporter
CCR
glycosidase
CRISPR/Cas9
Proton pump
Glutathione Peroxidase
FKBP
Cannabinoid Receptor
Adenylyl Cyclase
PYK2
UGT
Antifection
BCRP
Transferase
Bcl-6
Stearoyl-CoA Desaturase (SCD)
ACK1
Lipid
RAAS
Serotonin Transporter
CSF-1R
Acyltransferase
Y Box Binding Protein 1
Arginase
gp120/CD4
Progesterone Receptor
CaSR
Photosensitizer
Liver X Receptor
NAMPT
Ephrin Receptor
GST
Reverse Transcriptase
Aromatase
Lipase
Cell Cycle Arrest
Orphan Receptor
DUB
S1P Receptor
VDA
DNA
ATP Citrate Lyase
Hydroxylase
Sigma receptor
Chloride channel
MyD88
Cysteine Protease
Prolyl Endopeptidase (PREP)
FABP
LDL
Opioid Receptor
MAGL
Epoxide Hydrolase
PKM
LPL Receptor
P2X Receptor
Thrombopoietin Receptor
Androgen Receptor
Indoleamine 2,3-Dioxygenase (IDO)
Methionine Adenosyltransferase (MAT)
Aquaporin
Cuproptosis
Discoidin Domain Receptor (DDR)
Protease-activated Receptor
Kinesin
Advanced Glycation End Products
Necroptosis
Stemness kinase
IDO
Annexin A
Phosphorylase
AAK1 (AP2 associated kinase 1)
Na-K-Cl cotransporter
Bombesin Receptor
hCE
LPA Receptor
BMI-1
AhR
Melanin-concentrating Hormone Receptor (MCHR)
DHFR
Reductase
DNA Alkylation
FOXO
TAM Receptor
Vitamin
PGC-1α