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L-Serine-O-sulfate potassium
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Catalog No. T218097 Copy Product Info
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L-Serine-O-sulfate potassium inhibits serine racemase (Srr). It can alleviate the increase in NO levels, phosphorylation of nNOS at Ser847, PKC-dependent phosphorylation of GluN1 at Ser896, and the development of mechanical allodynia in mice induced by chronic constriction injury (CCI). L-Serine-O-sulfate potassium is utilized in the study of peripheral neuropathy.
L-Serine-O-sulfate potassium
Cas No. 17436-02-1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | L-Serine-O-sulfate potassium inhibits serine racemase (Srr). It can alleviate the increase in NO levels, phosphorylation of nNOS at Ser847, PKC-dependent phosphorylation of GluN1 at Ser896, and the development of mechanical allodynia in mice induced by chronic constriction injury (CCI). L-Serine-O-sulfate potassium is utilized in the study of peripheral neuropathy. |
| In vivo | In 4-week-old male ICR mice, L-Serine-O-sulfate potassium (LSOS) (10 nmol; intrathecal injection; twice daily; for 4 days) significantly inhibited neuropathic pain-related mechanical allodynia induced by chronic constriction injury (CCI) and the corresponding biochemical marker changes. |
| Molecular Weight | 224.25 |
| Formula | C3H7KNO6S |
| Cas No. | 17436-02-1 |
| Smiles | C([C@@H](C(O)=O)N)OS(=O)(=O)O.[K] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Related Tags: L-Serine-O-sulfate potassium in vivo | L-Serine-O-sulfate potassium formula | L-Serine-O-sulfate potassium molecular weight
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