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IFNAR2 Protein, Human, Recombinant (aa 27-243, His)
(Synonyms: β receptor10, β receptor 2, IFN-α/β R2, IFN-α, IFN-R-2, IFN-R, IFNbR2, IFNARB, IFNAR2, IFN-alpha/beta R2, IFN-alpha, IFNABR, IFN α/β R2) Copy Product InfoSynonyms: β receptor10, β receptor 2, IFN-α/β R2, IFN-α, IFN-R-2, IFN-R, IFNbR2, IFNARB, IFNAR2, IFN-alpha/beta R2, IFN-alpha, IFNABR, IFN α/β R2
Catalog No. TMPK-00889 Copy Product Info
Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. IFNAR2 Protein, Human, Recombinant (aa 27-243, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 25.8 kDa and the accession number is P48551-2.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $44 | 7-10 days | 7-10 days | |
| 10 µg | $68 | 7-10 days | 7-10 days | |
| 20 µg | $108 | 7-10 days | 7-10 days | |
| 50 µg | $198 | 7-10 days | 7-10 days | |
| 100 µg | $347 | 7-10 days | 7-10 days | |
| 200 µg | $628 | 7-10 days | 7-10 days | |
| 500 µg | $1,400 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Human IFN alpha/beta R2, His Tag captured on CM5 Chip via anti-his antibody can bind Human IFN alpha 1, hFc Tag with an affinity constant of 11.90 nM as determined in SPR assay. |
| Description | Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. IFNAR2 Protein, Human, Recombinant (aa 27-243, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 25.8 kDa and the accession number is P48551-2. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | P48551-2 |
| Construction | Ile27-Lys243 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | β receptor10, β receptor 2, IFN-α/β R2, IFN-α, IFN-R-2, IFN-R, IFNbR2, IFNARB, IFNAR2, IFN-alpha/beta R2, IFN-alpha, IFNABR, IFN α/β R2 |
| Research Background | Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. |
| Molecular Weight | 25.8 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: IFNAR2 Protein, Human, Recombinant (aa 27-243, His) chemical structure | IFNAR2 Protein, Human, Recombinant (aa 27-243, His) molecular weight
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