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XCT0135908

Catalog No. T35159 CAS 300837-31-4

Synonyms: XCT 0135908, XCT-0135908

XCT0135908 is a selectivity agonist of RXR -Nurr1 over a broad range of other RXR dimerization partners but with a rather low potency.

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XCT0135908, CAS 300837-31-4

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

XCT0135908 is a selectivity agonist of RXR -Nurr1 over a broad range of other RXR dimerization partners but with a rather low potency.

Synonyms	XCT 0135908, XCT-0135908
Molecular Weight	345.39
Formula	C21H19N3O2
CAS No.	300837-31-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Preparation of 4-amino substituted condensed pyrimidine compounds as selective PDE4 inhibitors useful in treatment of diseases By Konetzki, Ingo; Jakob, Florian; Craan, Tobias; Hesslinger, Christian From PCT Int. Appl. (2014), WO 2014117947 A1 20140807. | Language: English, Database: CAPLUS 2. Selective PDE4 B inhibition and improvement in cognition in subjects with brain injury By Gurney, Mark E.; Atkins, Collen M.; Adaikkalasamy, David J.; Dietrich, W. Dalton From U.S. Pat. Appl. Publ. (2014), US 20140121221 A1 20140501. | Language: English, Database: CAPLUS 3. Treatment of neurodegenerative diseases using retinoid X receptor (RXR)-selective agonists By Burstein, Ethan S.; Olsson, Roger; McFarland, Krista From PCT Int. Appl. (2013), WO 2013020966 A1 20130214. | Language: English, Database: CAPLUS 4. Treatment of neurodegenerative diseases using retinoid X receptor (RXR)-selective agonists By Burstein, Ethan S.; Olsson, Roger; McFarland, Krista From Eur. Pat. Appl. (2013), EP 2556827 A1 20130213. | Language: English, Database: CAPLUS

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

XCT0135908 300837-31-4 XCT 0135908 XCT-0135908 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.