Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Thalidomide-O-amido-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].
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Description | Thalidomide-O-amido-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1]. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
Synonyms | Thalidomide-NH-PEG2-C2-NH2 |
Molecular Weight | 404.42 |
Formula | C19H24N4O6 |
CAS No. | 2093416-32-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Thalidomide-PEG2-C2-NH2 2093416-32-9 Others Thalidomide-PEG-2-C2-NH2 Thalidomide PEG2 C2 NH2 Thalidomide-NH-PEG2-C2-NH2 ThalidomidePEG2C2NH2 inhibitor inhibit