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TASP0390325

Catalog No. T28926   CAS 1642187-96-9
Synonyms: TASP-0390325, TASP 0390325

TASP0390325, a potent and orally active V1B receptor antagonist, has antidepressant and anxiolytic activities in rodents.

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TASP0390325 Chemical Structure
TASP0390325, CAS 1642187-96-9
Pack Size Availability Price/USD Quantity
1 mg 5 days $ 49.00
50 mg 6-8 weeks $ 789.00
100 mg 6-8 weeks $ 1,280.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description TASP0390325, a potent and orally active V1B receptor antagonist, has antidepressant and anxiolytic activities in rodents.
Synonyms TASP-0390325, TASP 0390325
Molecular Weight 554.44
Formula C25H30Cl2FN5O4
CAS No. 1642187-96-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

TargetMolReferences and Literature

1. Koga K, Nagai Y, Hanyu M, Yoshinaga M, Chaki S, Ohtake N, Ozaki S, Zhang MR, Suhara T, Higuchi M. High-contrast PET imaging of vasopressin V(1B) receptors with a novel radioligand, (11)C-TASP699. J Nucl Med. 2017 Apr 27. pii: jnumed.116.188698. doi: 10.2967/jnumed.116.188698. [Epub ahead of print] PubMed PMID: 28450560. 2. Iijima M, Yoshimizu T, Shimazaki T, Tokugawa K, Fukumoto K, Kurosu S, Kuwada T, Sekiguchi Y, Chaki S. Antidepressant and anxiolytic profiles of newly synthesized arginine vasopressin V1B receptor antagonists: TASP0233278 and TASP0390325. Br J Pharmacol. 2014 Jul;171(14):3511-25. doi: 10.1111/bph.12699. PubMed PMID: 24654684; PubMed Central PMCID: PMC4105937.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

TASP0390325 1642187-96-9 TASP-0390325 TASP 0390325 inhibitor inhibit

 

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