Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Poloppin is a protein-protein interactions modulator of the mitotic polo-like kinases that acts by targeting mutant KRAS. It works synergistically with Crizotinib, an inhibitor of the c-MET receptor, against mutant KRAS-expressing cancer cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 65.00 | |
5 mg | 35 days | $ 193.00 | |
10 mg | 35 days | $ 353.00 | |
25 mg | 35 days | $ 784.00 |
Description | Poloppin is a protein-protein interactions modulator of the mitotic polo-like kinases that acts by targeting mutant KRAS. It works synergistically with Crizotinib, an inhibitor of the c-MET receptor, against mutant KRAS-expressing cancer cells. |
Targets&IC50 | PLK:26.9 μM (IC50), Protein-Protein interaction via the Polo-box domain (PBD):26.9 μM (Kd) |
Molecular Weight | 438.24 |
Formula | C20H15BrF3NO2 |
CAS No. | 683808-78-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Poloppin 683808-78-8 inhibitor inhibit