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Bradykinin potentiator-5

Catalog No. T25173   CAS 30505-63-6
Synonyms: BPP-5a\, BPP 5a\, BPP5a\

Bradykinin potentiator-5 is a peptide inflammatory mediator, causes blood vessels to dilate (enlarge), and therefore causes blood pressure to fall.

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Bradykinin potentiator-5 Chemical Structure
Bradykinin potentiator-5, CAS 30505-63-6
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Bradykinin potentiator-5 is a peptide inflammatory mediator, causes blood vessels to dilate (enlarge), and therefore causes blood pressure to fall.
Synonyms BPP-5a\, BPP 5a\, BPP5a\
Molecular Weight 611.7
Formula C30H41N7O7
CAS No. 30505-63-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Balaguer JM, Yu C, Byrne JG, Ball SK, Petracek MR, Brown NJ, Pretorius M. Contribution of endogenous bradykinin to fibrinolysis, inflammation, and blood product transfusion following cardiac surgery: a randomized clinical trial. Clin Pharmacol Ther. 2013 Apr;93(4):326-34. doi: 10.1038/clpt.2012.249. Epub 2012 Dec 24. PubMed PMID: 23361105; PubMed Central PMCID: PMC4031681. 2. Jiang Y, Xi X, Ge L, Yang N, Hou X, Ma J, Ma C, Wu Y, Guo X, Li R, Zhou M, Wang L, Chen T, Shaw C. Bradykinin-related peptides (BRPs) from skin secretions of three genera of phyllomedusine leaf frogs and their comparative pharmacological effects on mammalian smooth muscles. Peptides. 2014 Feb;52:122-33. doi: 10.1016/j.peptides.2013.12.013. Epub 2014 Jan 3. PubMed PMID: 24394432. 3. Shi D, Luo Y, Du Q, Wang L, Zhou M, Ma J, Li R, Chen T, Shaw C. A novel bradykinin-related dodecapeptide (RVALPPGFTPLR) from the skin secretion of the Fujian large-headed frog (Limnonectes fujianensis) exhibiting unusual structural and functional features. Toxins (Basel). 2014 Sep 29;6(10):2886-98. doi: 10.3390/toxins6102886. PubMed PMID: 25268979; PubMed Central PMCID: PMC4210874. 4. Uzawa A, Mori M, Taniguchi J, Kuwabara S. Modulation of the kallikrein/kinin system by the angiotensin-converting enzyme inhibitor alleviates experimental autoimmune encephalomyelitis. Clin Exp Immunol. 2014 Nov;178(2):245-52. doi: 10.1111/cei.12413. PubMed PMID: 24996009; PubMed Central PMCID: PMC4233374.

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Keywords

Bradykinin potentiator-5 30505-63-6 Bradykinin potentiator5 BPP-5a\ Bradykinin potentiator 5 BPP 5a\ BPP5a\ inhibitor inhibit

 

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