Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(S)-TCO-PEG3-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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Description | (S)-TCO-PEG3-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 344.45 |
Formula | C17H32N2O5 |
CAS No. | T18676 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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(S)-TCO-PEG3-amine T18676 Others (S)TCOPEG3amine (S) TCO PEG3 amine TCO-PEG3-amine (S)-TCO-PEG-3-amine inhibitor inhibit