keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
α-Hemolysin (Staphylococcus aureus), a polypeptide virulence factor of Staphylococcus aureus, disrupts host cell plasma membranes. Upon binding to the cell surface, its monomers create a homoheptamic prepore, which evolves into a mature transmembrane pore, facilitating K+ and Ca2+ ion transport that induces necrotic death in target cells [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | Inquiry | |
50 mg | Inquiry | Inquiry |
Description | α-Hemolysin (Staphylococcus aureus), a polypeptide virulence factor of Staphylococcus aureus, disrupts host cell plasma membranes. Upon binding to the cell surface, its monomers create a homoheptamic prepore, which evolves into a mature transmembrane pore, facilitating K+ and Ca2+ ion transport that induces necrotic death in target cells [1]. |
In vitro | α-Hemolysin (Staphylococcus aureus) induces IL-1β secretion and caspase-1 activation in THP-1 cells via NLRP3 inflammasome-dependent caspase-1 activation [1]. Additionally, α-hemolysin (Staphylococcus aureus)(1 µg/mL, 4h) triggers cell death in derivatives of THP cells, which requires host NLRP3 signaling but is independent of caspase-1 activation and IL-1β secretion [1]. |
Molecular Weight | N/A |
CAS No. | 94716-94-6 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
α-Hemolysin (Staphylococcus aureus) 94716-94-6 inhibitor inhibit