Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Isoprostanes are prostaglandin (PG)-like products of free-radical induced lipid peroxidation. Although the isoprostanes derived from arachidonic acid are the best characterized, many other polyunsaturated fatty acids can form isoprostanes. (±)5-iPF2α-VI is one of dozens of possible stereo- and regioisomeric isoprostanes which can be formed from arachidonic acid. To date, the most extensively studied of these is 8-isoprostane (8-epi-PGF2α, iPF2α-III). However, 8-isoprostane is a minor isoprostane constituent when compared to some of the other isomers which form in natural conditions of oxidative stress. (±)5-iPF2α-VI is an isoprostane from the unique Type VI class of isoprostanes. This class has been shown to be one of the major isoprostane products, in contrast to 8-isoprostane. In addition to being produced in greater abundance than 8-isoprostane, Type VI isoprostanes form internal lactones, which facilitates their extraction and purification from biological samples.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 35 days | $ 148.00 | |
25 μg | 35 days | $ 335.00 | |
50 μg | 35 days | $ 633.00 | |
100 μg | 35 days | $ 1,120.00 |
Description | Isoprostanes are prostaglandin (PG)-like products of free-radical induced lipid peroxidation. Although the isoprostanes derived from arachidonic acid are the best characterized, many other polyunsaturated fatty acids can form isoprostanes. (±)5-iPF2α-VI is one of dozens of possible stereo- and regioisomeric isoprostanes which can be formed from arachidonic acid. To date, the most extensively studied of these is 8-isoprostane (8-epi-PGF2α, iPF2α-III). However, 8-isoprostane is a minor isoprostane constituent when compared to some of the other isomers which form in natural conditions of oxidative stress. (±)5-iPF2α-VI is an isoprostane from the unique Type VI class of isoprostanes. This class has been shown to be one of the major isoprostane products, in contrast to 8-isoprostane. In addition to being produced in greater abundance than 8-isoprostane, Type VI isoprostanes form internal lactones, which facilitates their extraction and purification from biological samples. |
Synonyms | (±)5-iPF2α-VI |
Molecular Weight | 354.487 |
Formula | C20H34O5 |
CAS No. | 179094-11-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: 50 mg/mL
DMSO: 50 mg/mL
Ethanol: 50 mg/mL
PBS (pH 7.2): 0.5 mg/mL
You can also refer to dose conversion for different animals. More
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(±)5-iPF2α-VI 179094-11-2 (±)5-iPF-2α-VI 5-iPF2α-VI 5-iPF2alpha-VI 5-iPF2a-VI (±)5iPF2αVI (±)5 iPF2α VI inhibitor inhibit