RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc)

Name: RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc)
Brand: TargetMol
SKU: TMPK-00351
Rating: 4.5 (1 reviews)

(Synonyms: TRANCER, TNFRSF11A, Receptor activator of NF-KB, Rank, PDB2, OSTS, OPTB7, ODFR, NF-KB, NFKB, LOH18CR1, FEO, CD265) Copy Product Info

Synonyms: TRANCER, TNFRSF11A, Receptor activator of NF-KB, Rank, PDB2, OSTS, OPTB7, ODFR, NF-KB, NFKB, LOH18CR1, FEO, CD265

Catalog No. TMPK-00351 Copy Product Info

TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in gliomas, which affects apoptotic activity and focus formation thereby contributing to the molecular pathogenesis of gliomas. RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 46.85 kDa and the accession number is Q9Y6Q6-1.

RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc)

Pack Size	Price	USA Stock	Global Stock
5 µg	$58	7-10 days	7-10 days
10 µg	$92	7-10 days	7-10 days
20 µg	$148	7-10 days	7-10 days
50 µg	$289	7-10 days	7-10 days
100 µg	$487	7-10 days	7-10 days
200 µg	$883	7-10 days	7-10 days
500 µg	$1,950	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human RANKL, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human TNFRSF11A, hFc Tag with the EC50 of 8.5ng/ml determined by ELISA.
Description	TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in gliomas, which affects apoptotic activity and focus formation thereby contributing to the molecular pathogenesis of gliomas. RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 46.85 kDa and the accession number is Q9Y6Q6-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q9Y6Q6-1
Construction	Ile30-Pro212
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	TRANCER, TNFRSF11A, Receptor activator of NF-KB, Rank, PDB2, OSTS, OPTB7, ODFR, NF-KB, NFKB, LOH18CR1, FEO, CD265
Research Background	TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in gliomas, which affects apoptotic activity and focus formation thereby contributing to the molecular pathogenesis of gliomas.

Chemical Properties

Molecular Weight

46.85 kDa (predicted). Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Dose Conversion

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Tech Support

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Keywords

PDB-2PDB 2OPTB-7OPTB 7CD-265CD 265

Related Tags: RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc) chemical structure | RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc) molecular weight