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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3043 | Ruxolitinib phosphate | INC424 , INCB018424 , INC 424 phosphate , Ruxolitinib (INCB-18424) phosphate , INCB018424 phosphate | Mitophagy , JAK , Autophagy |
Ruxolitinib phosphate (INCB018424)(INCB018424 phosphate) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. |