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Dexamisole

Catalog No. T25315 CAS 14769-74-5

Synonyms: d-Tetramisole, d Tetramisole

Dexamisole is an inactive isomer of levamisole (a stereospecific ALP activity inhibitor).

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Dexamisole, CAS 14769-74-5

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Dexamisole is an inactive isomer of levamisole (a stereospecific ALP activity inhibitor).

Synonyms	d-Tetramisole, d Tetramisole
Molecular Weight	204.29
Formula	C11H12N2S
CAS No.	14769-74-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Bertucci C, Tedesco D, Fabini E, Di Pietra AM, Rossi F, Garagnani M, Del Borrello E, Andrisano V. Determination of levamisole and tetramisole in seized cocaine samples by enantioselective high-performance liquid chromatography and circular dichroism detection. J Chromatogr A. 2014 Oct 10;1363:150-4. doi: 10.1016/j.chroma.2014.07.069. Epub 2014 Jul 29. PubMed PMID: 25124228. 2. Casale JF, Colley VL, Legatt DF. Determination of phenyltetrahydroimidazothiazole enantiomers (Levamisole/Dexamisole) in illicit cocaine seizures and in the urine of cocaine abusers via chiral capillary gas chromatography-flame-ionization detection: clinical and forensic perspectives. J Anal Toxicol. 2012 Mar;36(2):130-5. doi: 10.1093/jat/bkr025. PubMed PMID: 22337783. 3. Dolezalová M, Tkaczyková M. LC determination of the enantiomeric purity of levamisole using stationary phase with bonded naphthylethylcarbamoylated-beta-cyclodextrin. J Pharm Biomed Anal. 2001 Jun;25(3-4):407-15. PubMed PMID: 11377020. 4. Anagnostou F, Plas C, Nefussi JR, Forest N. Role of beta-GP-derived Pi in mineralization via ecto-alkaline phosphatase in cultured fetal calvaria cells. J Cell Biochem. 1996 Aug;62(2):262-74. PubMed PMID: 8844406.

Dose Conversion

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Dexamisole 14769-74-5 d-Tetramisole d Tetramisole inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.